Evidence map›Paper›PMID 30875946›Full record

ReviewBiosensors2019

Enzyme-Based Electrochemical Biosensors for Microfluidic Platforms to Detect Pharmaceutical Residues in Wastewater.

Ana Lucia Campaña, Sergio Leonardo Florez, Mabel Juliana Noguera, Olga P Fuentes, Paola Ruiz Puentes, Juan C Cruz, Johann F Osma

Open access · goldAbstract readReview
In one paragraph

Review in Biosensors, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 96 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ana Lucia CampañaDepartment of Electrical and Electronics Engineering, Universidad de los Andes, Cra. 1E No. 19a-40, Bogotá, DC 111711, Colombia. al.campana10@uniandes.edu.co.ORCID 0000-0001-8374-4942
Sergio Leonardo FlorezDepartment of Electrical and Electronics Engineering, Universidad de los Andes, Cra. 1E No. 19a-40, Bogotá, DC 111711, Colombia. sl.florez10@uniandes.edu.co.ORCID 0000-0002-5723-1382
Mabel Juliana NogueraDepartment of Electrical and Electronics Engineering, Universidad de los Andes, Cra. 1E No. 19a-40, Bogotá, DC 111711, Colombia. mj.noguera10@uniandes.edu.co.ORCID 0000-0001-6782-9399
Olga P FuentesDepartment of Electrical and Electronics Engineering, Universidad de los Andes, Cra. 1E No. 19a-40, Bogotá, DC 111711, Colombia. op.fuentes@uniandes.edu.co.
Paola Ruiz PuentesDepartment of Biomedical Engineering, Universidad de los Andes, Cra. 1E No. 19a-40, Bogotá, DC 111711, Colombia. p.ruiz@uniandes.edu.co.
Juan C CruzDepartment of Biomedical Engineering, Universidad de los Andes, Cra. 1E No. 19a-40, Bogotá, DC 111711, Colombia. jc.cruz@uniandes.edu.co.ORCID 0000-0002-7790-7546
Johann F OsmaDepartment of Electrical and Electronics Engineering, Universidad de los Andes, Cra. 1E No. 19a-40, Bogotá, DC 111711, Colombia. jf.osma43@uniandes.edu.co.ORCID 0000-0003-2928-3406
Universidad de Los Andes · CO

Funding

Departamento Administrativo de Ciencia, Tecnología e Innovación Formación de capital humano de alto nivel para el departamento del Cesar
6 · The paper itself

Abstract

Emerging water pollutants such as pharmaceutical contaminants are suspected to induce adverse effects to human health. These molecules became worrisome due to their increasingly high concentrations in surface waters. Despite this alarming situation, available data about actual concentrations in the environment is rather scarce, as it is not commonly monitored or regulated. This is aggravated even further by the absence of portable and reliable methods for their determination in the field. A promising way to tackle these issues is the use of enzyme-based and miniaturized biosensors for their electrochemical detection. Here, we present an overview of the latest developments in amperometric microfluidic biosensors that include, modeling and multiphysics simulation, design, manufacture, testing, and operation methods. Different types of biosensors are described, highlighting those based on oxidases/peroxidases and the integration with microfluidic platforms. Finally, issues regarding the stability of the biosensors and the enzyme molecules are discussed, as well as the most relevant approaches to address these obstacles.

Indexed as

Biosensing TechniquesElectrochemical TechniquesEnzymes, ImmobilizedMicrofluidicsWastewaterWater PollutantsEnzymes, ImmobilizedWastewaterWater Pollutantsbiosensorselectrochemistryenzymesmicrofluidicspharmaceutical residues

Identifiers

PMID30875946
PMCPMC6468553
OpenAlexW2922516682

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.