Evidence map›Paper›PMID 30875838›Full record

ArticleInternational journal of molecular sciences2019

Methoxsalen and Bergapten Prevent Diabetes-Induced Osteoporosis by the Suppression of Osteoclastogenic Gene Expression in Mice.

Ju Ri Ham, Ra-Yeong Choi, Hae-In Lee, Mi-Kyung Lee

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. The Correlation of Type 2 Diabetes Status with Bone Mineral Density in Middle-Aged Adults.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020
    Article
  12. Simultaneous Determination of Three Coumarins inJournal of analytical methods in chemistry · 2020
    Article
  13. Impact of Diabetes Mellitus on Bone Health.International journal of molecular sciences · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ju Ri HamDepartment of Food and Nutrition, Sunchon National University, Suncheon 57922, Korea. punsu05@nate.com.
Ra-Yeong ChoiDepartment of Food and Nutrition, Sunchon National University, Suncheon 57922, Korea. fkdud1304@naver.com.
Hae-In LeeMokpo Marin Food-Industry Research Center, Mokpo 58621, Korea. hich2731@nate.com.
Mi-Kyung LeeDepartment of Food and Nutrition, Sunchon National University, Suncheon 57922, Korea. leemk@sunchon.ac.kr.ORCID 0000-0002-6064-5295
Sunchon National University · KR

Funding

National Research Foundation of Korea NRF-2015R1C1A2A01052146
6 · The paper itself

Abstract

This study evaluated whether bergapten and methoxsalen could prevent diabetes-induced osteoporosis and its underlying mechanism. For 10 weeks, bergapten or methoxsalen (0.02%,

Indexed as

5-MethoxypsoralenAlkaline PhosphataseAnimalsBone DensityDiabetes Mellitus, ExperimentalDiet, High-FatDisease Models, AnimalGene Expression RegulationHumansMaleMethoxsalenMiceNFATC Transcription FactorsOsteocalcinOsteogenesisOsteoporosis5-MethoxypsoralenAcp5 protein, mouseAlkaline PhosphataseMethoxsalenNfatc1 protein, mouseNFATC Transcription FactorsOsteocalcinRANK LigandStreptozocinTartrate-Resistant Acid PhosphataseTnfsf11 protein, mousebergaptenbone microarchitecturediabetesmethoxsalenosteoporosis

Identifiers

PMID30875838
PMCPMC6471636
OpenAlexW2922344828

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.