Evidence map›Paper›PMID 30875751›Full record

ArticleMarine drugs2019

'Messy' Processing of χ-conotoxin MrIA Generates Homologues with Reduced hNET Potency.

Rebekah Ziegman, Andreas Brust, Prerna Jha, Fernanda C Cardoso, Richard J Lewis, Paul F Alewood

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Rebekah ZiegmanInstitute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia. r.ziegman@uq.edu.au.
Andreas BrustInstitute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia. a.brust@imb.uq.edu.au.
Prerna JhaInstitute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia. p.jha@imb.uq.edu.au.
Fernanda C CardosoInstitute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia. f.caldascardoso@uq.edu.au.ORCID 0000-0002-0068-9974
Richard J LewisInstitute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia. r.lewis@uq.edu.au.
Paul F AlewoodInstitute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia. p.alewood@imb.uq.edu.au.
The University of Queensland · AU

Funding

National Health and Medical Research Council Program Grant APP1072113
6 · The paper itself

Abstract

Integrated venomics techniques have shown that variable processing of conotoxins from

Indexed as

Amino AcidsAmino Acid SequenceAnimalsCell LineChlorocebus aethiopsConotoxinsConus SnailCOS CellsFluorenesHumansMollusk VenomsNorepinephrine Plasma Membrane Transport ProteinsPeptidesAmino AcidsConotoxinsFluorenesMollusk VenomsN(alpha)-fluorenylmethyloxycarbonylamino acidsNorepinephrine Plasma Membrane Transport ProteinsPeptidesbioactivityconotoxinMrIANorepinephrine Transporter Inhibitor (NET)peptides

Identifiers

PMID30875751
PMCPMC6470548
OpenAlexW2922071990

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.