ArticleThe British journal of radiology2019
Stiffness of prostate gland measured by transrectal real-time shear wave elastography for detection of prostate cancer: a feasibility study.
Article in The British journal of radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 38 citations in OpenAlex.
- Diagnostic value of intravoxel incoherent motion-based virtual MR elastography for differentiating prostate cancer from benign prostate lesion.Abdominal radiology (New York) · 2026Article
- Physiological elasticity and topography modulateiScience · 2026Article
- ECM (collagen) mediated signaling drives the emergence of androgen independence in prostate cancer cells.Biochemistry and biophysics reports · 2026Article
- Antifibrotic therapy for Lower Urinary Tract Symptoms secondary to Benign Prostatic Hyperplasia.Prostate cancer and prostatic diseases · 2026Review
- Diagnostic Value of Multiparametric Transrectal Ultrasound in Patients with Suspected Carcinoma of Prostate: A Tertiary Care Centre Experience.The Indian journal of radiology & imaging · 2026Article
- Wide-field quantitative micro-elastography of freshly excised human prostate.Biomedical optics express · 2025Article
- A comparative study of histotripsy parameters for the treatment of fibrotic ex-vivo human benign prostatic hyperplasia tissue.Scientific reports · 2024Article
- Research on the mean maximum Young's modulus value as a new diagnostic parameter for prostate cancer.Scientific reports · 2024Article
- A Comparative Study of Histotripsy Parameters for the Treatment of Fibrotic ex-vivo Human Benign Prostatic Hyperplasia Tissue.Research square · 2024Article
- Review
- The utility of two-dimensional shear wave elastography for predicting prostate cancer: a preliminary study.Ultrasonography (Seoul, Korea) · 2023Article
- Matrix stiffness induces epithelial-to-mesenchymal transition via Piezo1-regulated calcium flux in prostate cancer cells.iScience · 2023Article
- Collagen-Specific Molecular Magnetic Resonance Imaging of Prostate Cancer.International journal of molecular sciences · 2022Article
- The Extracellular Matrix Stiffening: A Trigger of Prostate Cancer Progression and Castration Resistance?Cancers · 2022Review
- Alternatives for MRI in Prostate Cancer Diagnostics-Review of Current Ultrasound-Based Techniques.Cancers · 2022Review
- Miniaturized optical fiber probe for prostate cancer screening.Biomedical optics express · 2021Article
- Quantitative ultrasound shear wave elastography (USWE)-measured tissue stiffness correlates with PIRADS scoring of MRI and Gleason score on whole-mount histopathology of prostate cancer: implications for ultrasound image-guided targeting approach.Insights into imaging · 2021Article
- Quantification of penile fat infiltration using the mDIXON Quant sequence: a pilot study on the correlation with penis hardness and erectile dysfunction.The British journal of radiology · 2021Article
- Advanced ultrasound in the diagnosis of prostate cancer.World journal of urology · 2021Article
- Characterisation of Prostate Lesions Using Transrectal Shear Wave Elastography (SWE) Ultrasound Imaging: A Systematic Review.Cancers · 2021Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aimed to evaluate the value of the Young's modulus obtained by transrectal real-time shear wave elastography (SWE) for detection of prostate cancer (PCa).
methods215 patients underwent SWE in six identical planes before biopsy guided with transrectal ultrasonography. The Young's modulus of the entire prostate gland was defined as the mean of the results in these planes. The measurements were compared with the pathological results, the prostate specific antigen (PSA), and the Gleason score (GS) after biopsy.
resultsThe Young's modulus of elasticity, including the maximum Young's modulus (Emax), the mean Young's modulus (Emean), and the minimum Young's modulus (Emin), were significantly higher in malignant lesions than those in benign lesions (all
conclusionThe Young's modulus of entire prostate gland can be used to differentiate benign from malignant prostatic lesions. There were higher Young's modulus of elasticity and higher risk of malignant lesions. Meanwhile, higher Young's modulus correlated with higher PSA and GS. ADVANCES IN KNOWLEDGE: This study indicates SWE can detect PCa by quantified the stiffness of entire prostate gland whether the lesions have been visible or not on gray-scale and Doppler ultrasound.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.