Evidence map›Paper›PMID 30875185›Full record

ReviewJBRA assisted reproduction2019

Environmental toxins and the impact of other endocrine disrupting chemicals in women's reproductive health.

Mauri José Piazza, Almir Antônio Urbanetz

Abstract readReview
In one paragraph

Review in JBRA assisted reproduction, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. The Association of Bisphenol A and Phthalates with Risk of Breast Cancer: A Meta-Analysis.International journal of environmental research and public health · 2021
    Pooled it
  4. Pooled it
  5. Review
  6. Ovarian toxic effects of micro- and nanoplastics (Review).Experimental and therapeutic medicine · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Signs of Potential Androgen Excess Across the Lifespan in a US-based Digital Cohort Study.The Journal of clinical endocrinology and metabolism · 2025
    Article
  12. Review
  13. Knowledge and attitudes of pregnant women about endocrine disruptors.Revista da Associacao Medica Brasileira (1992) · 2025
    Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mauri José PiazzaTocogynecology Department, Universidade Federal do Paraná - UFPR - Curitiba (PR), Brazil.
Almir Antônio UrbanetzTocogynecology Department, Universidade Federal do Paraná - UFPR - Curitiba (PR), Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review aimed to look into agents and mechanisms characterized as endocrine disrupting chemicals (EDCs). These agents are known to cause several harmful effects to the reproductive system of women and wildlife. There is a wide range of chemicals, developed for commercial use mainly in agriculture, which may cause endocrine disruption. Numerous studies show evidence of environmental contamination. However, no one is being held liable for the damages. The most important potentially harmful agents are identified and described, along with the different effects they have on the female genital area. Brazil is a large consumer of pesticides and others chemicals that may interfere with a normal women's life. We analyzed and described the mode of action and the impacts of different EDCs (bisphenols, phthalates, atrazine, polychlorinated and polybrominated biphenyls, DDT-dichlorodiphenyltrichloroethane; DDE-dichlorodiphenyldichloroethylene; DDD-dichlorodiphenyldichloroethane; and DES-diethylstilbestrol) on the genital area, ovarian steroidogenesis, polycystic ovary syndrome, endometriosis, the structure of the uterus and the vagina, and on the formation of leiomyomas.

Indexed as

Reproductive HealthEndocrine DisruptorsEnvironmental ExposureFemaleGenital Diseases, MaleHazardous SubstancesHumansOvaryEndocrine DisruptorsHazardous Substancesendocrine disrupting chemicalsenvironmental pollutionenvironmental toxicantshuman reproductionreproductive health

Identifiers

PMID30875185
PMCPMC6501744

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.