SynthesisQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2019
Quality of life is substantially worse for community-dwelling older people living with frailty: systematic review and meta-analysis.
Synthesis in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 115 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
115 citing papers in PubMed, 4 syntheses or guidelines pooled it, 221 citations in OpenAlex.
- The impact of integrated care on quality of life in community-dwelling older adults with frailty: A systematic review and mixed method synthesis.The Journal of frailty & aging · 2026Pooled it
- Associations between meeting 24-hour movement guidelines and health-related quality of life in older adults: a systematic review and meta-analysis.BMC public health · 2025Pooled it
- Comparison of Questionnaire and Performance-Based Physical Frailty Scales to Predict Survival and Health-Related Quality of Life in Patients With Heart Failure.Journal of the American Heart Association · 2023Pooled it
- Information provision for stroke survivors and their carers.The Cochrane database of systematic reviews · 2021Pooled it
- Enabling health and maintaining independence for older people at home: the 'HomeHealth' Randomised Controlled Trial.Health technology assessment (Winchester, England) · 2026Trial
- A Home-Based Online Psychoeducation Programme on Subjective Well-Being Amongst Community-Dwelling Older Adults With Frailty: A Pilot Randomised Controlled Trial.International journal of older people nursing · 2026Trial
- Serratus plane block versus standard of care for pain control after totally endoscopic aortic valve replacement: a double-blind, randomized controlled, superiority trial.Regional anesthesia and pain medicine · 2024Trial
- Trial
- Network Analysis of Health-Related Quality of Life by Frailty Status Among Korean Older Adults: Korea National Health and Nutrition Examination Survey (KNHANES) 2019-2021.Geriatrics & gerontology international · 2026Article
- Longitudinal associations of chronic pain and sleep quality with frailty progression in community-dwelling older adults.Aging clinical and experimental research · 2026Article
- Association between segmental and whole-body phase angle from bioelectrical impedance analysis and the physical function in community-dwelling older adults.Scientific reports · 2026Article
- Mediterranean Diet Adherence and Ultraprocessed Food Consumption in Relation to Body Composition and Muscle Function Outcomes among Midlife and Older Women: NHANES 2007-2018.Current developments in nutrition · 2026Article
- Patterns of Vulnerability: Frailty, Multimorbidity, and Physical Health-Related Quality of Life in Institutionalised Older Adults.Healthcare (Basel, Switzerland) · 2026Article
- Modifiable lifestyle factors and their association with depression and quality of life in community-dwelling older adults: a multicriteria index analysis.Scientific reports · 2026Article
- Relationship among frailty, nutrition, depression and quality of life in the older population.BMC geriatrics · 2026Article
- Reciprocal relationship between intrinsic capacity and social activity influenced by gender in advanced middle-aged adults in South Korea.BMC public health · 2026Article
- The mediating role of social networks and safety perceptions in the frailty-quality of life relationship among older people in rural and urban regions of Ghana.BMC public health · 2026Article
- Frailty as an indicator of adverse health outcomes in rheumatoid arthritis: a multicenter cross-sectional study.Arthritis research & therapy · 2026Article
- Using Indoor Movement Complexity in Smart Homes to Detect Frailty in Older Adults: Multiple-Methods Case Series Study.JMIR aging · 2026Article
- Supportive environments moderate the relationship between frailty and life satisfaction in older adults: evidence from the China health and retirement longitudinal study (CHARLS).BMC geriatrics · 2025Article
55 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeFrailty is an important predictor of adverse health events in older people, and improving quality of life (QOL) is increasingly recognised as a focus for services in this population. This systematic review synthesised evidence of the relationship between frailty and QOL in community-dwelling older people, with an emphasis on how this relationship varied across QOL domains.
methodsWe conducted a systematic review with meta-analysis. We searched five databases for reports of QOL in older people with frailty and included studies based on pre-defined criteria. We conducted meta-analyses comparing "frail" and "not frail" groups for each QOL scale where data were available. We compared pooled results to distribution-based and known-group differences to enhance interpretation. We summarised reported cross-sectional and longitudinal analyses.
resultsTwenty-two studies (24,419 participants) were included. There were medium or larger standardised mean differences for 24 of 31 QOL scales between frail and not frail groups, with worse QOL for frail groups. These scales encompassed constructs of health-related quality of life as well as psychological and subjective well-being. There were similar findings from mean difference meta-analyses and within-study analyses.
conclusionsThe association between frailty and lower QOL across a range of constructs is clear and often substantial. Future research should establish whether causal mechanisms link the constructs, which aspects of QOL are most important to older people with frailty, and investigate their tractability. Services focused on measuring and improving QOL for older people with frailty should be introduced.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.