ArticleEcotoxicology (London, England)2019
Chronic toxicity and biochemical response of Apis cerana cerana (Hymenoptera: Apidae) exposed to acetamiprid and propiconazole alone or combined.
Article in Ecotoxicology (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 67 citations in OpenAlex.
- Binary Mixture of Neonicotinoid-Pyrethroid Insecticide: Impact on Survival, Cognitive Learning, and Memory inBiology · 2025Article
- Article
- Combined Toxic Effects of Lead and Glyphosate onInsects · 2024Article
- Effects of common co-occurring pesticides (a neonicotinoid and fungicide) on honey bee colony health in a semi-field study.Heliyon · 2024Article
- The fungicide azoxystrobin causes histopathological and cytotoxic changes in the midgut of the honey bee Apis mellifera (Hymenoptera: Apidae).Ecotoxicology (London, England) · 2023Article
- Toxicity assessment of SARS-CoV-2-derived peptides in combination with a mix of pollutants on zebrafish adults: A perspective study of behavioral, biometric, mutagenic, and biochemical toxicity.The Science of the total environment · 2023Article
- Biochemical responses, feeding and survival in the solitary bee Osmia bicornis following exposure to an insecticide and a fungicide alone and in combination.Environmental science and pollution research international · 2023Article
- Gut microbiota composition and gene expression changes induced in theFrontiers in physiology · 2023Article
- Combined transcriptome and metabolite profiling analyses provide insights into the chronic toxicity of carbaryl and acetamiprid to Apis mellifera larvae.Scientific reports · 2022Article
- Adsorption and Photocatalytic Degradation of Pesticides into Nanocomposites: A Review.Molecules (Basel, Switzerland) · 2022Review
- Article
- Effects of Acetamiprid at Low and Median Lethal Concentrations on the Development and Reproduction of the Soybean AphidInsects · 2022Article
- Review
- Review on Sublethal Effects of Environmental Contaminants in Honey Bees (International journal of environmental research and public health · 2021Review
- Interaction of Insecticides and Fungicides in Bees.Frontiers in insect science · 2021Review
- Article
- Propiconazole induces abnormal behavior and oxidative stress in zebrafish.Environmental science and pollution research international · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
Acetamiprid and ergosterol-inhibiting fungicide (EBI) are frequently applied to many flowering plants, while honey bees are pollinating agents or pollinators of the flowers. Hence honey bees are often exposed to these pesticides. But until now, the effects of theses combinations at field-realistic doses on honey bee health have been poorly investigated. In this study, we explore the synergistic mortality and some physiological effects in surviving honey bees after chronic oral exposure to acetamiprid and/or propiconazole in the laboratory. The results indicated that chronic combined exposure to acetamiprid and propiconazole produced a significant synergistic effect on mortality both for newly emerged bees (50% mortality in 7.2 days) and forager bees (50% mortality in 4.8 days). Honey bee weight of newly emerged bees was decreased after feeding food with a field concentration of acetamiprid and propiconazole, alone or combined for 10 days. Combination of acetamiprid and propiconazole also modulated the activities of P450s, GST and CAT in newly emerged bees and forager bees than either alone, but neither pesticide affected the activity of AChE. These results show that chronic combined exposure to pesticides of relatively low toxicity may caused severely physiological disruptions that could be potentially damaging for the honey bees.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.