SynthesisInternational urogynecology journal2019
Sacral neuromodulation treating chronic pelvic pain: a meta-analysis and systematic review of the literature.
Synthesis in International urogynecology journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05851742 (Effects of Myofascial Release With and Without Electrical Stimulation on Pain and Functionality in Women With Chronic Pelvic Pain), which is not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Myofascial Release With and Without Electrical Stimulation on Pain and Functionality in Women With Chronic Pelvic Pain
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Evaluation and management of chronic anorectal and pelvic pain syndromes: Italian Society of Colorectal Surgery (SICCR) position statement.Techniques in coloproctology · 2024Guideline
- Sacral Nerve Modulation Alleviates Neuropathic Pelvic Pain Through Modulation of the Spinal Immune Microenvironment and Microglial Activation.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2026Article
- Surgical Management of Urinary-Symptom-Dominant Endometriosis: Addressing Persistent Voiding Dysfunction and Pelvic Floor Factors.International urogynecology journal · 2026Review
- Sacral neuromodulation for the treatment of idiopathic non-obstructive urinary retention: A long-term follow-up case report.Surgical neurology international · 2026Article
- Long-Term Outcomes of Sacral Neuromodulation for Refractory Interstitial Cystitis/Bladder Pain Syndrome: A Retrospective Cohort Study.Journal of clinical medicine · 2025Article
- Good long-term results of sacral neuromodulation for endometriosis related chronic pelvic pain.BMC women's health · 2025Article
- How Intravesical Platelet-Rich Plasma Can Help Patients with Interstitial Cystitis/Bladder Pain Syndrome: A Comprehensive Scoping Review.International urogynecology journal · 2024Article
- Neuromodulation Techniques in Chronic Refractory Coccydynia: A Narrative Review.Pain and therapy · 2024Review
- Updates in pelvic neuromodulation: the role of pelvic neuromodulation in pelvic disorders.Frontiers in urology · 2024Review
- Sacral neuromodulation in endometriosis - A promising treatment option for chronic pelvic pain.Acta obstetricia et gynecologica Scandinavica · 2023Article
- Neuromodulation for Management of Chronic Pelvic Pain: A Comprehensive Review.Pain and therapy · 2022Review
- Broaden Horizons: The Advancement of Interstitial Cystitis/Bladder Pain Syndrome.International journal of molecular sciences · 2022Review
- Current advances in neuromodulation techniques in urology practices: A review of literature.Turkish journal of urology · 2021Article
- Computer-Assisted Lead Placement for Peripheral Nerve Evaluation Test in a Candidate for Sacral Neuromodulation.International neurourology journal · 2020Article
- Medications used to treat bladder disorders may alter effects of neuromodulation.Neurourology and urodynamics · 2020Article
- Outcomes of sacral neuromodulation for chronic pelvic pain: a Finnish national multicenter study.Techniques in coloproctology · 2020Article
- Commentary on: Sacral neuromodulation treating chronic pelvic pain: a meta-analysis and systematic review of the literature.International urogynecology journal · 2019Article
- Sacral neuromodulation implanted patients: Patient concerns during the COVID-19 pandemic and practical modifications.Therapeutic advances in urologyArticle
- A comprehensive treatment algorithm for chronic pelvic pain patients: A perspective review and future guidelines.Women's health (London, England)Review
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introduction and hypothesisSacral neuromodulation (SNM) is gaining popularity as a treatment option for chronic pelvic pain (CPP). Our hypothesis is that SNM is effective in improving CPP.
methodsA systematic search was conducted through September 2018. Peer-reviewed studies using pre- and postpain intensity scores were selected. The primary outcome was pain improvement on a 10-point visual analog scale (VAS) (adjusted or de novo) in patients with CPP. Secondary outcomes included comparing SNM approaches and etiologies and evaluating lower urinary tract symptoms (LUTS).
resultsFourteen of 2175 studies, evaluating 210 patients, were eligible for further analysis. The overall VAS pain score improvement was significant [weighted mean difference (WMD) -4.34, 95% confidence interval (CI) = -5.22, to-3.64, p < 0.0001)]. Regarding SNM approach, both standard and caudal approaches had significant reduction in pain scores: WMD -4.32, CI 95% = -5.32, to -3.31 (p < 0.001) for the standard approach, compared with WMD -4.63, 95% CI = -6.57 to -2.69 (P < 0.001), for the caudal approach (p = 0.75). While significant improvement in pain was observed both in patients with and without interstitial cystitis/bladder pain syndrome (IC/BPS), the observed improvement was lower in patients with (WMD -4.13, CI 95% -5.36 to -2.90 versus without (WMD -5.72, CI 95% = -6.18, to-5.27) IC/BPS (p = 0.02). SNM was effective in treating voiding symptoms (frequency, urgency, nocturia) associated with IC/BPS (all p < 0.01).
conclusionsSNM is an effective therapy for CPP in both IC/BSP and non-IC/BSP patients, with better results in non-IC/BSP patients. Outcomes of the antegrade caudal approach were comparable with the standard retrograde approach.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.