Evidence map›Paper›PMID 30874595›Full record

ArticleScientific reports2019

Estrogen deficiency impairs integrin α

Ivor P Geoghegan, David A Hoey, Laoise M McNamara

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 50 citations in OpenAlex.

  1. Review
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  9. Mechanosignaling in Osteoporosis: When Cells Feel the Force.International journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Ivor P GeogheganMechanobiology and Medical Device Research Group (MMDRG), Biomedical Engineering, National University of, Ireland, Galway, Ireland.ORCID 0000-0001-5029-0315
David A HoeyCentre for Research in Medical Devices (CÚRAM), National University of Ireland, Galway, Ireland.ORCID 0000-0001-5898-0409
Laoise M McNamaraMechanobiology and Medical Device Research Group (MMDRG), Biomedical Engineering, National University of, Ireland, Galway, Ireland. Laoise.McNamara@nuigalway.ie.ORCID 0000-0002-5050-9230
Ollscoil na Gaillimhe – University of Galway · IEScience Foundation Ireland · IE

Funding

European Research Council 336882
6 · The paper itself

Abstract

The integrin α

Indexed as

AnimalsCell LineCyclooxygenase 2EstrogensFocal AdhesionsIntegrin alphaVbeta3Integrin beta3Mechanotransduction, CellularMiceOsteocytesOsteogenesisParacrine CommunicationRANK LigandSignal TransductionCyclooxygenase 2EstrogensIntegrin alphaVbeta3Integrin beta3RANK Ligand

Identifiers

PMID30874595
PMCPMC6420496
OpenAlexW2922256857

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.