Evidence map›Paper›PMID 30874358›Full record

ReviewImmunological reviews2019

T-bet

James J Knox, Arpita Myles, Michael P Cancro

Abstract readReview
In one paragraph

Review in Immunological reviews, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

86 citing papers in PubMed, 128 citations in OpenAlex.

  1. Trial
  2. Review
  3. B cell-intrinsic CXCR3 drives efficient generation of ectopic pulmonary germinal center responses to influenza A virus infection.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Article
  5. Article
  6. The multilayered identity of B cell memory.Cellular & molecular immunology · 2026
    Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. IgMScientific reports · 2025
    Article
  12. Review
  13. Article
  14. Effect of Age on Xenobiotic-Induced Autoimmunity.bioRxiv : the preprint server for biology · 2025
    Article
  15. Review
  16. Multimodal profiling of transplant rejection: Discerning the forest from the trees.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2025
    Article
  17. Article
  18. Review
  19. Article
  20. Review

26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

James J KnoxDepartment of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Arpita MylesDepartment of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Michael P CancroDepartment of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.ORCID 0000-0002-8659-3227
University of Pennsylvania · US

Funding

Multidisciplinary Training in Cardiovascular BiologyT32HL007954 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI DAVIES, PETER FRANCIS · 2000 to 2019
$9.9M
Immune System Development and RegulationT32AI055428 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ALLMAN, DAVID M, OLIVER, PAULA MARIA · 2003 to 2025
$4.2M
Mechanistic studies of BLyS-mediated modulation in HIV-1 Env-specific antibody responsesR01AI118691 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI CANCRO, MICHAEL PAUL · 2015 to 2019
$3.4M
Plasma Cell PrimingR21AI133998 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ALLMAN, DAVID M, CANCRO, MICHAEL PAUL · 2017 to 2018
$443k
NHLBI NIH HHS T32 HL007954NIAID NIH HHS R01 AI118691NIAID NIH HHS R21 AI133998NIAID NIH HHS T32 AI055428
6 · The paper itself

Abstract

B cells expressing the transcription factor T-bet have emerged as participants in a number of protective and pathogenic immune responses. T-bet

Indexed as

AnimalsAutoantibodiesAutoimmunityB-LymphocytesB-Lymphocyte SubsetsCell DifferentiationCytokinesHumansImmunologic MemoryLymphocyte ActivationMiceSignal TransductionT-bet Transcription FactorT-Box Domain ProteinsToll-Like ReceptorsAutoantibodiesCytokinesT-bet Transcription FactorT-Box Domain ProteinsToll-Like Receptorshumoral autoimmunityintracellular pathogensmemory B cellsplasma cellsT-bet+ B cellstissue-resident memory B cells

Identifiers

PMID30874358
PMCPMC6626622
OpenAlexW2921136352

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.