ArticleArchives of rheumatology2018
Clinical and Serologic Characteristics of Systemic Lupus Erythematosus in the Arab World: A Pooled Analysis of 3,273 Patients.
Article in Archives of rheumatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Mortality and survival in patients with systemic lupus erythematosus in the Middle East and North Africa: a systematic review and meta-analysis.Rheumatology international · 2026Pooled it
- Clinical outcomes and prognostic factors in lupus nephritis: impact of remission on renal and overall survival in a single-center study.BMC nephrology · 2026Article
- The Spectrum and Temporal Trends of Glomerular Diseases in Saudi Arabia: A Systematic Review of Biopsy-Based Studies.International journal of nephrology · 2026Review
- Systemic lupus erythematosus: Auditing standard of care in Qatar.Qatar medical journal · 2026Article
- Unveiling the Financial Burden of Systemic Lupus Erythematosus Management in Saudi Arabia: Insights from a Single-Center Study.Healthcare (Basel, Switzerland) · 2025Article
- The impact of familial autoimmunity and familial lupus on the clinical presentations and disease outcomes of SLE patients in the United Arab Emirates.BMC rheumatology · 2025Article
- Autoimmune Health Crisis: An Inclusive Approach to Addressing Disparities in Women in the United States.International journal of environmental research and public health · 2024Review
- Insights into systemic lupus erythematosus: a retrospective observational study of clinical features, autoantibodies, and gender-related differences.Rheumatology international · 2024Observational
- Pattern of systemic lupus erythematosus in NIGERIA: a multicentre descriptive hospital-based study.Clinical rheumatology · 2023Article
- Mortality in a cohort of Egyptian systemic lupus erythematosus patients: A comparison with African, Arabic, and Mediterranean studies.Archives of rheumatology · 2023Article
- Clinical Manifestations of Systemic Lupus Erythematosus in a Tertiary Center in Saudi Arabia.Cureus · 2023Article
- Risk factors of significant relapse and appropriate maintenance therapy strategy in SLE-associated immune thrombocytopenia.Therapeutic advances in chronic disease · 2023Article
- Antinuclear antibody-negative systemic lupus erythematosus: How many patients and how to identify?Archives of rheumatology · 2022Article
- Immunogenetic Profiling of SLE and LN among Jordanian Patients.Journal of personalized medicine · 2022Article
- Major histocompatibility complex (MHC) associations with diseases in ethnic groups of the Arabian Peninsula.Immunogenetics · 2021Review
- Quality of Life of Patients with Systemic Lupus Erythematosus in Eastern Saudi Arabia: A Cross-sectional Study.Saudi journal of medicine & medical sciencesArticle
Corrections and comments
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Authors and funding
1 author.
Funding
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Abstract
objectivesThis study aims to describe the clinical and immunological characteristics of systemic lupus erythematosus in the Arab world. MATERIALS AND
methodsWe searched PubMed and Google Scholar for observational studies describing the clinical and serologic features of systemic lupus erythematosus in adult patients in the Arab world. We used the search terms "lupus in Arabs" and the names of individual Arab countries. Twenty-two articles from 11 countries including 3,273 patients (349 males, 2,924 females; mean age 28.9 years) met the inclusion criteria and were analyzed. Studies that reported on either clinical or serologic data in adult patients were included.
resultsThe mean age at disease onset was 28.9 years. The female to male ratio was 8.34:1. The most common clinical manifestations were arthralgia/arthritis (81.1%), anemia (55.6%), fatigue (53.4%), malar rash (53.1%) and renal manifestations (50.4%). Antinuclear antibodies were present in 97.2%, anti-double stranded deoxyribonucleic acid in 74.1%, anti-Ro/Sjögren syndrome A in 50.5%, anti-ribonucleoprotein in 43.5%, anti-Smith in 40.7% and anti-La/Sjögren syndrome B in 29.2%. The mortality rate was 7.6%. The frequency of various clinical and immunological manifestations varied between different regions.
conclusionSystemic lupus erythematosus displays several different clinical and serologic characteristics, both among different Arab populations and in comparison to other ethnic groups.
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