Evidence map›Paper›PMID 30873793›Full record

SynthesisAnnals of global health2018

Potential Co-exposure to Arsenic and Fluoride and Biomonitoring Equivalents for Mexican Children.

Jorge H Limón-Pacheco, Mónica I Jiménez-Córdova, Mariana Cárdenas-González, Ilse M Sánchez Retana, María E Gonsebatt, Luz M Del Razo

Abstract readSystematic Review
In one paragraph

Synthesis in Annals of global health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  7. The Development of FeGels (Basel, Switzerland) · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Circulating miRNAs Associated with Arsenic Exposure.Environmental science & technology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jorge H Limón-PachecoDepartamento de Medicina Genómica y Toxicología Ambiental, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, MX.
Mónica I Jiménez-CórdovaDepartamento de Toxicología, Centro de Investigación y de Estudios Avanzados del IPN, MX.
Mariana Cárdenas-GonzálezRenal Division, Brigham and Women's Hospital, Harvard Institute of Medicine, Boston, MA, US.
Ilse M Sánchez RetanaDepartamento de Medicina Genómica y Toxicología Ambiental, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, MX.
María E GonsebattDepartamento de Medicina Genómica y Toxicología Ambiental, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, MX.
Luz M Del RazoDepartamento de Toxicología, Centro de Investigación y de Estudios Avanzados del IPN, MX.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMexico is included in the list of countries with concurrent arsenic and fluoride contamination in drinking water. Most of the studies have been carried out in the adult population and very few in the child population. Urinary arsenic and urinary fluoride levels have been accepted as good biomarkers of exposure dose. The Biomonitoring Equivalents (BE) values are useful tools for health assessment using human biomonitoring data in relation to the exposure guidance values, but BE information for children is limited.

methodsWe conducted a systematic review of the reported levels of arsenic and fluoride in drinking water, urinary quantification of speciated arsenic (inorganic arsenic and its methylated metabolites), and urinary fluoride levels in child populations. For BE values, urinary arsenic and fluoride concentrations reported in Mexican child populations were revised discussing the influence of factors such as diet, use of dental products, sex, and metabolism.

resultsApproximately 0.5 and 6 million Mexican children up to 14 years of age drink water with arsenic levels over 10 μg/L and fluoride over 1.5 mg/L, respectively. Moreover, 40% of localities with arsenic levels higher than 10 μg/L also present concurrent fluoride exposure higher than 1.5 mgF/L. BE values based in urinary arsenic of 15 μg/L and urinary fluoride of 1.2 mg/L for the environmentally exposed child population are suggested.

conclusionsAn actual risk map of Mexican children exposed to high levels of arsenic, fluoride, and both arsenic and fluoride in drinking water was generated. Mexican normativity for maximum contaminant level for arsenic and fluoride in drinking water should be adjusted and enforced to preserve health. BE should be used in child populations to investigate exposure.

Indexed as

Drinking WaterArsenicChildEnvironmental ExposureEnvironmental MonitoringFluoridesHumansMexicoRisk AssessmentWater Pollutants, ChemicalWater QualityArsenicDrinking WaterFluoridesWater Pollutants, Chemical

Identifiers

PMID30873793
PMCPMC6748235

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.