Evidence map›Paper›PMID 30873792›Full record

ArticleAnnals of global health2018

Prenatal Exposure to Nitrogen Oxides and its Association with Birth Weight in a Cohort of Mexican Newborns from Morelos, Mexico.

Jessica Mendoza-Ramirez, Albino Barraza-Villarreal, Leticia Hernandez-Cadena, Octavio Hinojosa de la Garza, José Luis Texcalac Sangrador, Luisa Elvira Torres-Sanchez, Marlene Cortez-Lugo, Consuelo Escamilla-Nuñez, Luz Helena Sanin-Aguirre, Isabelle Romieu

Open access · goldAbstract read
In one paragraph

Article in Annals of global health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Jessica Mendoza-RamirezInstituto Nacional de Salud Pública, Av. Universidad # 655, Col. Santa María Ahuacatitlán, C.P. 62100 Cuernavaca, Morelos, MX.
Albino Barraza-VillarrealInstituto Nacional de Salud Pública, Av. Universidad # 655, Col. Santa María Ahuacatitlán, C.P. 62100 Cuernavaca, Morelos, MX.
Leticia Hernandez-CadenaInstituto Nacional de Salud Pública, Av. Universidad # 655, Col. Santa María Ahuacatitlán, C.P. 62100 Cuernavaca, Morelos, MX.
Octavio Hinojosa de la GarzaCentro de Investigación en Materiales Avanzados S.C., Complejo Industrial Chihuahua, Avenida Miguel de Cervantes 120, C.P. 31109 Chihuahua, Chih, MX.
José Luis Texcalac SangradorInstituto Nacional de Salud Pública, Av. Universidad # 655, Col. Santa María Ahuacatitlán, C.P. 62100 Cuernavaca, Morelos, MX.
Luisa Elvira Torres-SanchezInstituto Nacional de Salud Pública, Av. Universidad # 655, Col. Santa María Ahuacatitlán, C.P. 62100 Cuernavaca, Morelos, MX.
Marlene Cortez-LugoInstituto Nacional de Salud Pública, Av. Universidad # 655, Col. Santa María Ahuacatitlán, C.P. 62100 Cuernavaca, Morelos, MX.
Consuelo Escamilla-NuñezInstituto Nacional de Salud Pública, Av. Universidad # 655, Col. Santa María Ahuacatitlán, C.P. 62100 Cuernavaca, Morelos, MX.
Luz Helena Sanin-AguirreFacultad de Enfermería y Nutriología, Universidad Autónoma de Chihuahua, Circuito Universitario Campus II, C.P. 31240 Chihuahua, Chih, MX.
Isabelle RomieuInstituto Nacional de Salud Pública, Av. Universidad # 655, Col. Santa María Ahuacatitlán, C.P. 62100 Cuernavaca, Morelos, MX.
Instituto Nacional de Salud Pública · MXAutonomous University of Chihuahua · MX

Funding

Omega fatty acid supplementation and allergic diseases in childrenR01HD058818 · NICHD · MEXICO NATIONAL INSTITUTE OF PUBLIC HLTH · PI ROMIEU, ISABELLE · 2009 to 2012
$768k
NICHD NIH HHS R01 HD058818
6 · The paper itself

Abstract

backgroundThe Child-Mother binomial is potentially susceptible to the toxic effects of pollutants because some chemicals interfere with placental transfer of nutrients, thus affecting fetal development, and create an increased the risk of low birth weight, prematurity and intrauterine growth restriction.

objectiveTo evaluate the impact of prenatal exposure to nitrogen oxides (NOx) on birth weight in a cohort of Mexican newborns. METHODOLOGY: We included 745 mother-child pair participants of the POSGRAD cohort study. Information on socio-demographic characteristics, obstetric history, health history and environmental exposure during pregnancy were readily available and the newborns' anthropometric measurements were obtained at delivery. Prenatal NOx exposure assessment was evaluated using a Land-Use Regression predictive models considering local monitoring from 60 sites on the State of Morelos. The association between prenatal exposure to NOx and birth weight was estimated using a multivariate linear regression models.

resultsThe average birth weight was 3217 ± 439 g and the mean of NOx concentration was 21 ppb (Interquartile range, IQR = 6.95 ppb). After adjusting for maternal age and other confounders, a significant birthweight reduction was observed for each IQR of NOx increase (ß = -39.61 g, 95% CI: -77.00; -2.21; p = 0.04).

conclusionsOur results provides evidence that prenatal NOx exposure has a negative effect on birth weight, which may influence the growth and future development of the newborn.

Indexed as

Environmental ExposureFetal Growth RetardationMaternal ExposurePremature BirthPrenatal Exposure Delayed EffectsAdultBirth WeightCohort StudiesFemaleFetal DevelopmentHumansInfant, NewbornMaleMexicoNeeds AssessmentNitrogen OxidesNitrogen Oxides

Identifiers

PMID30873792
PMCPMC6748222
OpenAlexW2883736414

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.