ArticleJournal of biomedical optics2019
Validation of combined Monte Carlo and photokinetic simulations for the outcome correlation analysis of benzoporphyrin derivative-mediated photodynamic therapy on mice.
Article in Journal of biomedical optics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Photosensitizer spatial heterogeneity and its impact on personalized interstitial photodynamic therapy treatment planning.Journal of biomedical optics · 2025Article
- Article
- Integrating clinical access limitations into iPDT treatment planning with PDT-SPACE.Biomedical optics express · 2023Article
- Photodynamic therapy in a pleural cavity using monte carlo simulations with 2D/3D Graphical Visualization.Global journal of cancer therapy · 2022Article
- Machine learning for real-time optical property recovery in interstitial photodynamic therapy: a stimulation-based study.Biomedical optics express · 2021Article
- FullMonteCUDA: a fast, flexible, and accurate GPU-accelerated Monte Carlo simulator for light propagation in turbid media.Biomedical optics express · 2019Article
- Treatment planning evolution: Comparing approaches in photodynamic and radiation therapies.Photochemistry and photobiologyReview
- A Monte Carlo simulation for Moving Light Source in Intracavity PDT.Proceedings of SPIE--the International Society for Optical EngineeringArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
We compare previously reported benzoporphyrin derivative (BPD)-mediated photodynamic therapy (PDT) results for reactive singlet oxygen concentration (also called singlet oxygen dose) on mice with simulations using a computational device, Dosie™, that calculates light transport and photokinetics for PDT in near real-time. The two sets of results are consistent and validate the use of the device in PDT treatment planning to predict BPD-mediated PDT outcomes in mice animal studies based on singlet oxygen dose, which showed a much better correlation with the cure index than the conventional light dose.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.