Evidence map›Paper›PMID 30873724›Full record

ArticleTransboundary and emerging diseases2019

Respiratory viruses identified in western Canadian beef cattle by metagenomic sequencing and their association with bovine respiratory disease.

Maodong Zhang, Janet E Hill, Champika Fernando, Trevor W Alexander, Edouard Timsit, Frank van der Meer, Yanyun Huang

Open access · bronzeAbstract read
In one paragraph

Article in Transboundary and emerging diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 108 citations in OpenAlex.

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  13. Prevalence of bovine respiratory disease viruses in calves from the central desert of Iran.Veterinary research forum : an international quarterly journal · 2025
    Article
  14. Article
  15. Article
  16. Influenza D virus infection in China, 2022-2023.Emerging microbes & infections · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Maodong ZhangDepartment of Veterinary Pathology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK, Canada.ORCID https://orcid.org/0000-0002-9565-3017
Janet E HillDepartment of Veterinary Microbiology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK, Canada.ORCID https://orcid.org/0000-0002-2187-6277
Champika FernandoDepartment of Veterinary Microbiology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK, Canada.
Trevor W AlexanderAgriculture and Agri-Food Canada, Lethbridge Research and Development Centre, Lethbridge, AB, Canada.
Edouard TimsitDepartment of Production Animal Health, University of Calgary, Calgary, AB, Canada.
Frank van der MeerDepartment of Ecosystem and Public Health, University of Calgary, Calgary, AB, Canada.
Yanyun HuangDepartment of Veterinary Pathology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK, Canada.
University of Saskatchewan · CAAlberta Health Services · CAUniversity of Calgary · CAUniversity of Lethbridge · CA

Funding

Alberta Livestock and Meat Agency Ltd., and Genome AlbertaChina Scholarship CouncilSaskatchewan Cattleman Association 20160092
6 · The paper itself

Abstract

Bovine respiratory disease (BRD) causes considerable economic losses in North America. The pathogenesis involves interactions between bacteria, viruses, environment and management factors. Primary viral infection can increase the risk of secondary fatal bacterial infection. The objective of this study was to use metagenomic sequencing to characterize the respiratory viromes of paired nasal swabs and tracheal washes from western Canadian feedlot cattle, with or without BRD. A total of 116 cattle (116 nasal swabs and 116 tracheal washes) were analysed. The presence of influenza D virus (IDV), bovine rhinitis A virus (BRAV), bovine rhinitis B virus (BRBV), bovine coronavirus (BCV) and bovine respiratory syncytial virus (BRSV) was associated with BRD. Agreement between identification of viruses in nasal swabs and tracheal washes was generally weak, indicating that sampling location may affect detection of infection. This study reported several viruses for the first time in Canada and provides a basis for further studies investigating candidate viruses important to the prevention of BRD.

Indexed as

MetagenomicsAnimalsAphthovirusCanadaCattleCattle DiseasesCoronavirus, BovineGenome, ViralRespiratory Syncytial Virus, BovineRespiratory Tract InfectionsRNA VirusesRNA Virus InfectionsThogotovirusbovine coronavirusbovine respiratory disease (BRD)bovine respiratory syncytial virusbovine rhinitis virusinfluenza D virusmetagenomic sequencingvirome

Identifiers

PMID30873724
PMCPMC7168561
OpenAlexW2921794314

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.