ArticleJournal of clinical and translational research2019
The effect of acute pain on executive function.
Article in Journal of clinical and translational research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 14 citations in OpenAlex.
- Reduced cerebral blood flow does not alter concurrent or post-intervention inhibitory control: evidence from a 3-h head-down tilt protocol in healthy young adults.Experimental brain research · 2026Article
- Pharmacological and behavioral pain treatment strategies for patients with opioid use disorder.Expert opinion on pharmacotherapy · 2025Review
- Effects of aging on experimentally induced pain perception during a distraction task.Scientific reports · 2025Article
- Working Memory Load-Dependent Cortical Mechanism of Distraction Analgesia in Healthy Individuals: An fNIRS Study.Journal of pain research · 2025Article
- Induced discomfort promotes executive function while walking with(out) an artificial neuromuscular impairment.Journal of neurophysiology · 2024Article
- A Comprehensive Description of the Anatomy and Histochemistry ofPharmaceuticals (Basel, Switzerland) · 2024Article
- Association between Self-Reported Pain, Cognition, and Neuropathology in Older Adults Admitted to an Outpatient Memory Clinic-A Cross-Sectional Study.Brain sciences · 2021Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimExecutive functions are high-level cognitive processes that allow a person to success-fully engage in an independent and self-fulfilling life. Previous literature indicates that chronic pain can affect executive function, but there are limited studies that investigate the effect of acute pain on executive function. The purpose of this study was to determine if acute pain affects executive function in recreationally active indi-viduals who sustained a musculoskeletal injury.
methodsTwenty-four recreationally active participants who presented with acute pain following a muscu-loskeletal injury underwent a neuropsychological battery within 72 hours of injury. Follow up testing occurred within two weeks from the initial testing session when participants were pain free. Pain intensity was measured using the Visual Analog Scale (VAS). The neuropsychological battery consisted of the following tests: Digit Span (DS), Rey Auditory Verbal Learning Test (RAVLT), and Trail Making Test B (TMT-B). The DS was bro-ken into two separate scores, the RAVLT four scores, and TMT-B one score. Seven paired samples t-tests were conducted using an adjusted alpha level of 0.007.
resultsParticipants had significantly improved scores when pain free in DS forwards (
conclusionsResults from this study suggest acute pain from musculoskeletal injuries may disrupt executive function. RELEVANCE FOR PATIENTS: Patients should be aware that there may be cognitive changes after a musculoskeletal injury. Knowing which cognitive domains may be impaired during acute pain could impact clinical practice and further benefit patients suffering from pain and its associated symptoms.
Indexed as
Identifiers
30873500PMC6412607W2607252069What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.