ArticleJournal of clinical and translational research2016
Understanding the responsiveness of nitric oxide to acute eccentric resistance exercise in elderly obese women.
Article in Journal of clinical and translational research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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10 authors.
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Abstract
BACKGROUND AND
aimThe aim of the present study was to examine nitrite concentration responses following eccentric resistance exercise (ERE) in elderly obese women. We also investigated the existence of high (HR) and low responders (LR) for nitrite and the possible differences with respect to creatine kinase (CK) response, metabolic and body composition variables.
methodsForty-nine elderly obese women completed an ERE session utilizing knee extensor exercise. LR for serum nitrite were defined as a ∆nitrite ≤ 20th percentile or 24.1 µmol/L and HR as a ∆nitrite > 20th percentile.
resultsTen subjects were classified as LR and the remaining as HR (n = 39). The HR group displayed greater nitrite concentration at 0 h, 3 h, 24 h and 48 h following the ERE as compared with the LR (
conclusionsElderly obese women classified as HR displayed higher nitrite responses to ERE. Thus, researchers should be aware of the presence of different responsiveness of nitrite to acute exercise to avoid misinterpretation of data and to identify the higher cardiovascular risk factor of those classified as LR. RELEVANCE FOR PATIENTS: The elevated NO up to 48 h following an ERE session may suggest an important protective cardiovascular effect. The higher body fat, cholesterol, LDL and lower upper limb fat-free mass in the LR group might represent a deleterious effect of lower serum levels of nitrite.
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30873464PMC6410657What OpenQuestion holds
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