ReviewJournal of clinical and translational research2015
Antibacterial photodynamic therapy: overview of a promising approach to fight antibiotic-resistant bacterial infections.
Review in Journal of clinical and translational research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05162417 (Efficacy of Some Different Photosensitizers in Photodynamic Inactivation of Periodontal Pathogens), which is not on this map. Cited by 135 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy of Some Different Photosensitizers in Photodynamic Inactivation of Periodontal Pathogens:A Randomized Clinical Trial
Who cites it
135 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Photodithazine-Mediated Antimicrobial Photodynamic Therapy: A Systematic Review of Efficacy and Applications.International journal of molecular sciences · 2025Pooled it
- Evaluating the Efficacy of Rose Bengal as a Photosensitizer in Antimicrobial Photodynamic Therapy AgainstInternational journal of molecular sciences · 2025Pooled it
- Photodynamic therapy and peri-implant diseases: a systematic review and meta-analysis.Frontiers in oral health · 2025Pooled it
- A Review of Evidence-Based Recommendations for Pericoronitis Management and a Systematic Review of Antibiotic Prescribing for Pericoronitis among Dentists: Inappropriate Pericoronitis Treatment Is a Critical Factor of Antibiotic Overuse in Dentistry.International journal of environmental research and public health · 2021Pooled it
- Conjugated Porphyrin Polymer With Superior Charge Transfer for Photodynamic-Immunomodulatory Prevention of CIED Infection in Diabetes.Advanced healthcare materials · 2026Article
- Laparoscopic Methylene Blue Photodynamic Therapy for Intraabdominal Infection: A Preclinical Feasibility Study in a Rabbit Model of Perforated Appendicitis.Lasers in surgery and medicine · 2026Article
- Antimicrobial Strategies in the Era of Resistance: It Is Too Early to Give Up Antibiotic Therapy.International journal of molecular sciences · 2026Review
- Effects of Mono- and Dicapsaicinoid Functionalization on the Physicochemical Properties and Antimicrobial Photodynamic Activity of Protoporphyrin IX.ChemMedChem · 2026Article
- Porphyrin and photodynamic therapy as tools against Acinetobacter baumannii.Antonie van Leeuwenhoek · 2026Review
- The Influence of the Central Metal (Zn) in the Porphyrin Skeleton on the Mechanism Induced by Photodynamic Therapy.Cancers · 2026Review
- Synthesis, In Vitro Antimicrobial Assessment, and Molecular Docking Investigations of Some Derived Compounds From Porphyrins.Journal of fluorescence · 2026Article
- Indolicidin-Decorated Photosensitizer for Enhanced Antibacterials and Accelerated Diabetic Wound Healing.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Sepiolite and Zirconia Nanoparticles Doped with Erythrosine: Adhesive Bond Strength and Antimicrobial Performance in Primary Carious Dentin.Pakistan journal of medical sciences · 2026Article
- Investigating the Efficacy of Various Photosensitizers and Irradiation Strategies in Antimicrobial Photodynamic Inactivation on Different Types of Microbes.International journal of molecular sciences · 2026Article
- Photodynamic Therapy in Dermatology.International journal of molecular sciences · 2026Review
- Effects of Supramolecular Interactions on E/Z-Isomerizations in Water and Their Importance for Biological Applications.Archiv der Pharmazie · 2026Review
- New isoxazole-based heterocyclic hybrids with dual antimicrobial and antioxidant bioactivity: integrated synthesis,RSC advances · 2026Article
- Lectin-Rose Bengal Conjugates for Targeted Photodynamic Inactivation of Pathogenic Bacteria.International journal of molecular sciences · 2026Article
- A conjugated polymer antimicrobial agent triggers metabolic cascade-mediated killing of carbapenem-resistantFrontiers in cellular and infection microbiology · 2026Article
- Photodynamic therapy with methylene blue effectively kills antibiotic resistant bacteria from pediatric patients with perforated appendicitis.Scientific reports · 2025Article
75 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antibacterial photodynamic therapy (APDT) has drawn increasing attention from the scientific society for its potential to effectively kill multidrug-resistant pathogenic bacteria and for its low tendency to induce drug resistance that bacteria can rapidly develop against traditional antibiotic therapy. The review summarizes the mechanism of action of APDT, the photosensitizers, the barriers to PS localization, the targets, the in vitro-, in vivo-, and clinical evidence, the current developments in terms of treating Gram-positive and Gram-negative bacteria, the limitations, as well as future perspectives.
Indexed as
Identifiers
30873451PMC6410618What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.