Evidence map›Paper›PMID 30873264›Full record

ArticleIranian journal of microbiology2018

Comparative effects of granulocyte-colony stimulating factor and colistin-alone or in combination on burn wound healing in

Somayeh Soleymanzadeh Moghadam, Zeinab Fagheei Aghmiyuni, Hassan Zaheri, Nastaran Arianpour, Mohammad Reza Danaeifard, Maryam Roham, Mahnoush Momeni

Open access · greenAbstract read
In one paragraph

Article in Iranian journal of microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Thioredoxin-mediated alteration of protein content and cytotoxicity ofExperimental biology and medicine (Maywood, N.J.) · 2022
    Article
  2. Topical Treatment of Second-Degree Burn Wounds withIranian journal of pathology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Somayeh Soleymanzadeh MoghadamAntimicrobial Resistance Research Center, Institute of Immunology and Infectious Diseases, Iran University of Medical Sciences, Tehran, Iran.
Zeinab Fagheei AghmiyuniDepartment of Microbiology and Immunology, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran.
Hassan ZaheriFaculty of Veterinary Medicine, Islamic Azad University, Garmsar branch, Garmsar, Iran.
Nastaran ArianpourAntimicrobial Resistance Research Center, Institute of Immunology and Infectious Diseases, Iran University of Medical Sciences, Tehran, Iran.
Mohammad Reza DanaeifardFaculty of Veterinary Medicine, Islamic Azad University, Garmsar branch, Garmsar, Iran.
Maryam RohamAntimicrobial Resistance Research Center, Institute of Immunology and Infectious Diseases, Iran University of Medical Sciences, Tehran, Iran.
Mahnoush MomeniBurn Research Center, Iran University of Medical Sciences, Tehran, Iran.
Iran University of Medical Sciences · IRKashan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesBurn wounds are one of the most important health problems all over the world because infection after burn can delay wound healing. Treating burn wounds with granulocyte-colony stimulating factor (G-CSF) is known to improve healing of injured tissue. In addition, colistin is prescribed as an effective treatment. The aim of this study was to evaluate the effect of G-CSF and colistin alone or in combination with G-CSF on wound healing of MATERIALS AND

methodsThis study was performed between January 2016 and April 2018. Burn wounds were experimentally induced in 36 mice. The wounds were inoculated with

resultsWound healing in the G-CSF plus colistin group was significantly higher than the control group and the G-CSF group (P = 0.023 and P = 0.033, respectively). In G-CSF+colistin group, the number of leukocytes was higher than the control group considerably (P = 0.007). On the 7

conclusionConcurrent consumption of G-CSF and antibiotics can control burn infection and enhance the immune system towards wound healing.

Indexed as

Acinetobacter baumanniiBurnColistinGranulocyte-colony stimulating factorWound infection

Identifiers

PMID30873264
PMCPMC6414739
OpenAlexW2922973540

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.