Evidence map›Paper›PMID 30873180›Full record

ArticleFrontiers in immunology2019

Species-Specific Structural Requirements of Alpha-Branched Trehalose Diester Mincle Agonists.

Alyson J Smith, Shannon M Miller, Cassandra Buhl, Robert Child, Margaret Whitacre, Roman Schoener, George Ettenger, David Burkhart, Kendal Ryter, Jay T Evans

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

  1. Synthetic Ligands of Myeloid C-Type Lectin Receptors.Chembiochem : a European journal of chemical biology · 2026
    Review
  2. Article
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  4. Article
  5. Article
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  7. Article
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  10. Article
  11. Article
  12. Advancing Adjuvants forFrontiers in immunology · 2021
    Review
  13. Review
  14. 6,6'-Aryl trehalose analogs as potential Mincle ligands.Bioorganic & medicinal chemistry · 2020
    Article
  15. Article
  16. Aryl Trehalose Derivatives as Vaccine Adjuvants forJournal of medicinal chemistry · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Alyson J SmithCenter for Translational Medicine, Missoula, MT, United States.
Shannon M MillerCenter for Translational Medicine, Missoula, MT, United States.
Cassandra BuhlCenter for Translational Medicine, Missoula, MT, United States.
Robert ChildCenter for Translational Medicine, Missoula, MT, United States.
Margaret WhitacreCenter for Translational Medicine, Missoula, MT, United States.
Roman SchoenerCenter for Translational Medicine, Missoula, MT, United States.
George EttengerCenter for Translational Medicine, Missoula, MT, United States.
David BurkhartCenter for Translational Medicine, Missoula, MT, United States.
Kendal RyterCenter for Translational Medicine, Missoula, MT, United States.
Jay T EvansCenter for Translational Medicine, Missoula, MT, United States.
University of Montana · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the ever present need for an effective

Indexed as

Adjuvants, ImmunologicAnimalsCell LineCord FactorsCytokinesHumansImmunity, CellularLectins, C-TypeMiceMolecular StructureMycobacterium tuberculosisStructure-Activity RelationshipTh17 CellsTrehaloseAdjuvants, ImmunologicCord FactorsCytokinesLectins, C-TypeTrehaloseadjuvantC type lectin receptormincle receptorMycobacterium tuberculosisTh17trehalose diester

Identifiers

PMID30873180
PMCPMC6403188
OpenAlexW2920090843

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.