Evidence map›Paper›PMID 30873102›Full record

ArticleFrontiers in neurology2019

Short-Term Effects of Focal Muscle Vibration on Motor Recovery After Acute Stroke: A Pilot Randomized Sham-Controlled Study.

Massimiliano Toscano, Claudia Celletti, Alessandro Viganò, Alberto Altarocca, Giada Giuliani, Tommaso B Jannini, Giulio Mastria, Marco Ruggiero, Ilaria Maestrini, Edoardo Vicenzini and 3 more

4 registry-linked trialsOpen access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03697525 nacompletednot on this map

Effects of Repeated (Focal) Muscle Vibration (rMV) on Motor Recovery After Acute Stroke: a Randomized Sham-controlled Study

TypeinterventionalSponsorUniversity of Roma La SapienzaRan2016 to 2020Enrolled22ConditionsAcute StrokeArmsVibration
NCT04289766 nacompletednot on this mapstarted 2020, after this paper: background citation

Effects of Focal Muscle Vibration on Upper Limb Function in Subacute Post-stroke Patients

TypeinterventionalSponsorRiphah International UniversityRan2020 to 2021Enrolled106ConditionsStroke, SubacuteArmsConventional Treatment, Focal Muscle Vibration (120Hz), Focal Muscle Vibration (60Hz)
NCT06296225 nacompletednot on this mapstarted 2024, after this paper: background citation

Effect of Vibratory Tendon Stimulation on Muscle Fatigue in the Acute Post-stroke Phase : Vibramain1

TypeinterventionalSponsorCentre Hospitalier Régional d'OrléansRan2024 to 2024Enrolled31ConditionsStroke, Stroke, Acute, FatigueArmsVibration
NCT06793566 nawithdrawnnot on this mapstarted 2025, after this paper: background citation

Effect of Tendon Vibrations on Motor Recovery of the Upper Limb in the Acute Phase of Stroke

TypeinterventionalSponsorCentre Hospitalier Régional d'OrléansRan2025 to 2026Enrolled0ConditionsAcute StrokeArmsRepeated Muscle Vibration (rMV)
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Trial
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Massimiliano ToscanoDepartment of Human Neurosciences, Sapienza University of Rome, Rome, Italy.
Claudia CellettiPhysical Medicine and Rehabilitation Division, Umberto I University Hospital, Rome, Italy.
Alessandro ViganòDepartment of Human Neurosciences, Sapienza University of Rome, Rome, Italy.
Alberto AltaroccaPhysical Medicine and Rehabilitation Division, Umberto I University Hospital, Rome, Italy.
Giada GiulianiDepartment of Human Neurosciences, Sapienza University of Rome, Rome, Italy.
Tommaso B JanniniDepartment of Human Neurosciences, Sapienza University of Rome, Rome, Italy.
Giulio MastriaDepartment of Human Neurosciences, Sapienza University of Rome, Rome, Italy.
Marco RuggieroDepartment of Human Neurosciences, Sapienza University of Rome, Rome, Italy.
Ilaria MaestriniDepartment of Human Neurosciences, Sapienza University of Rome, Rome, Italy.
Edoardo VicenziniDepartment of Human Neurosciences, Sapienza University of Rome, Rome, Italy.
Marta AltieriDepartment of Human Neurosciences, Sapienza University of Rome, Rome, Italy.
Filippo CamerotaPhysical Medicine and Rehabilitation Division, Umberto I University Hospital, Rome, Italy.
Vittorio Di PieroDepartment of Human Neurosciences, Sapienza University of Rome, Rome, Italy.
Sapienza University of Rome · ITPoliclinico Umberto I · ITFatebenefratelli Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Repetitive focal muscle vibration (rMV) is known to promote neural plasticity and long-lasting motor recovery in chronic stroke patients. Those structural and functional changes within the motor network underlying motor recovery occur in the very first hours after stroke. Nonetheless, to our knowledge, no rMV-based studies have been carried out in acute stroke patients so far, and the clinical benefit of rMV in this phase of stroke is yet to be determined. The aim of this randomized double-blind sham-controlled study is to investigate the short-term effect of rMV on motor recovery in acute stroke patients. Out of 22 acute stroke patients, 10 were treated with the rMV (vibration group-VG), while 12 underwent the sham treatment (control group-CG). Both treatments were carried out for 3 consecutive days, starting within 72 h of stroke onset; each daily session consisted of three 10-min treatments (for each treated limb), interspersed with a 1-min interval. rMV was delivered using a specific device (Cro®System, NEMOCO srl, Italy). The transducer was applied perpendicular to the target muscle's belly, near its distal tendon insertion, generating a 0.2-0.5 mm peak-to-peak sinusoidal displacement at a frequency of 100 Hz. All participants also underwent a daily standard rehabilitation program. The study protocol underwent local ethics committee approval (ClinicalTrial.gov NCT03697525) and written informed consent was obtained from all of the participants. With regard to the different pre-treatment clinical statuses, VG patients showed significant clinical improvement with respect to CG-treated patients among the NIHSS (

Indexed as

acute strokefocal muscle vibrationmotor recoveryneural plasticitystrokestroke rehabilitation

Identifiers

PMID30873102
PMCPMC6401608
OpenAlexW2916143236

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.