Sex-hormone producing adrenal tumors causing behavioral changes as the sole clinical sign in 3 cats.

Julia P Sumner, Sean E Hulsebosch, Robert M Dudley, Meredith L Miller, Galina M Hayes

Abstract readCase Reports

In one paragraph

Article in The Canadian veterinary journal = La revue veterinaire canadienne, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it

0cells of the map it votes in

4citing papers in PubMed

1.0field-weighted citation impact, top 24% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

Case Report: Trilostane therapy in a dog with recurrent adrenocortical carcinoma producing an array of steroid hormones.Frontiers in veterinary science · 2025
Article
Case report: Androgen-secreting adrenocortical tumors in eight cats.Frontiers in veterinary science · 2023
Article
A case of behavioral changes in a castrated male cat due to a functional adrenocortical adenoma producing testosterone and androstenedione.JFMS open reports
Article
Gynaecomastia in a male neutered cat with an adrenal tumour and associated hyperprogesteronism, hypercortisolism and hyperaldosteronism.JFMS open reports
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Julia P SumnerDepartment of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA (Sumner, Miller, Hayes); Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California-Davis, Davis, California 95616, USA (Hulsebosch); Medvet Columbus, Medical and Cancer Centers for Pets, Worthington, Ohio 43085, USA (Dudley).

Sean E HulseboschDepartment of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA (Sumner, Miller, Hayes); Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California-Davis, Davis, California 95616, USA (Hulsebosch); Medvet Columbus, Medical and Cancer Centers for Pets, Worthington, Ohio 43085, USA (Dudley).

Robert M DudleyDepartment of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA (Sumner, Miller, Hayes); Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California-Davis, Davis, California 95616, USA (Hulsebosch); Medvet Columbus, Medical and Cancer Centers for Pets, Worthington, Ohio 43085, USA (Dudley).

Meredith L MillerDepartment of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA (Sumner, Miller, Hayes); Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California-Davis, Davis, California 95616, USA (Hulsebosch); Medvet Columbus, Medical and Cancer Centers for Pets, Worthington, Ohio 43085, USA (Dudley).

Galina M HayesDepartment of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA (Sumner, Miller, Hayes); Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California-Davis, Davis, California 95616, USA (Hulsebosch); Medvet Columbus, Medical and Cancer Centers for Pets, Worthington, Ohio 43085, USA (Dudley).

Cornell University · USUniversity of California, Davis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three neutered cats with adrenocortical tumors that were presented with behavioral changes but no evidence of hyperaldosteronism or hypercortisolism are described. All 3 cats had resolution of their clinical signs following adrenalectomy. For neutered cats presenting with behavior changes, a sex-hormone secreting adrenal tumor should be considered as a differential diagnosis.

Indexed as

Adrenal Cortex NeoplasmsAdrenalectomyAdrenal Gland NeoplasmsAdrenocortical HyperfunctionAnimalsCat DiseasesCatsHyperaldosteronism

Identifiers

PMID30872855

PMCPMC6380267

OpenAlexW2979333848

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.