Evidence map›Paper›PMID 30872761›Full record

ArticleMucosal immunology2019

The alarmins IL-1 and IL-33 differentially regulate the functional specialisation of Foxp3

Fernando Alvarez, Roman Istomine, Mitra Shourian, Nils Pavey, Tho Al-Fakar Al-Aubodah, Salman Qureshi, Jörg H Fritz, Ciriaco A Piccirillo

Open access · hybridAbstract read
PubMed Publisher
In one paragraph

Article in Mucosal immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 67 citations in OpenAlex.

  1. Review
  2. IL-1 family cytokines in inflammation and immunity.Cellular & molecular immunology · 2025
    Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. IL-33 Signaling Inhibition Leads to a Preeclampsia-Like Phenotype in Pregnant Rats.American journal of reproductive immunology (New York, N.Y. : 1989) · 2024
    Article
  10. Inbred Mouse Models inJournal of fungi (Basel, Switzerland) · 2024
    Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Adaptive immunology ofFrontiers in immunology · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Fernando AlvarezDepartment of Microbiology and Immunology, McGill University, Montréal, QC, H3A 2B4, Canada.
Roman IstomineDepartment of Microbiology and Immunology, McGill University, Montréal, QC, H3A 2B4, Canada.
Mitra ShourianMeakins-Christie Laboratories, Department of Medicine and Division of Experimental Medicine, McGill University, Montréal, QC, H4A 3J1, Canada.
Nils PaveyDepartment of Microbiology and Immunology, McGill University, Montréal, QC, H3A 2B4, Canada.
Tho Al-Fakar Al-AubodahDepartment of Microbiology and Immunology, McGill University, Montréal, QC, H3A 2B4, Canada.
Salman QureshiMeakins-Christie Laboratories, Department of Medicine and Division of Experimental Medicine, McGill University, Montréal, QC, H4A 3J1, Canada.
Jörg H Fritz *Department of Microbiology and Immunology, McGill University, Montréal, QC, H3A 2B4, Canada.
Ciriaco A Piccirillo *Department of Microbiology and Immunology, McGill University, Montréal, QC, H3A 2B4, Canada. ciro.piccirillo@mcgill.ca.
McGill University Health Centre · CAMcGill University · CAChristie (Canada) · CA

Funding

CIHR 354133CIHR PJT-148821
6 · The paper itself

Abstract

CD4

Indexed as

AnimalsCell DifferentiationCells, CulturedCryptococcosisCryptococcus neoformansForkhead Transcription FactorsImmune ToleranceInterleukin-1Interleukin-1 Receptor-Like 1 ProteinInterleukin-33Lymphocyte ActivationMiceMice, Inbred BALB CMice, Inbred C57BLMice, KnockoutReceptors, Interleukin-1 Type IForkhead Transcription FactorsFoxp3 protein, mouseIL1R1 protein, mouseIl1rl1 protein, mouseInterleukin-1Interleukin-1 Receptor-Like 1 ProteinInterleukin-33Receptors, Interleukin-1 Type I

Identifiers

PMID30872761
OpenAlexW2921671942

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.