Evidence map›Paper›PMID 30872736›Full record

ArticleScientific reports2019

Scattering Assisted Imaging.

Marco Leonetti, Alfonso Grimaldi, Silvia Ghirga, Giancarlo Ruocco, Giuseppe Antonacci

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marco LeonettiCenter for Life Nano science @ Sapienza, Isituto Italiano di Tecnologia, Viale Regina Elena, 291, I-00161, Roma, Italy. marco.leonetti@iit.it.
Alfonso GrimaldiCenter for Life Nano science @ Sapienza, Isituto Italiano di Tecnologia, Viale Regina Elena, 291, I-00161, Roma, Italy.ORCID 0000-0001-5502-6740
Silvia GhirgaCenter for Life Nano science @ Sapienza, Isituto Italiano di Tecnologia, Viale Regina Elena, 291, I-00161, Roma, Italy.
Giancarlo RuoccoCenter for Life Nano science @ Sapienza, Isituto Italiano di Tecnologia, Viale Regina Elena, 291, I-00161, Roma, Italy.
Giuseppe AntonacciCenter for Life Nano science @ Sapienza, Isituto Italiano di Tecnologia, Viale Regina Elena, 291, I-00161, Roma, Italy.ORCID 0000-0001-5788-4853

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Standard imaging systems provide a spatial resolution that is ultimately dictated by the numerical aperture (NA) of the illumination and collection optics. In biological tissues, the resolution is strongly affected by scattering, which limits the penetration depth to a few tenths of microns. Here, we exploit the properties of speckle patterns embedded into a strongly scattering matrix to illuminate the sample at high spatial frequency content. Combining adaptive optics with a custom deconvolution algorithm, we obtain an increase in the transverse spatial resolution by a factor of 2.5 with respect to the natural diffraction limit. Our Scattering Assisted Imaging (SAI) provides an effective solution to increase the resolution when long working distance optics are needed, potentially paving the way to bulk imaging in turbid tissues.

Identifiers

PMID30872736
PMCPMC6418275

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.