Evidence map›Paper›PMID 30872652›Full record

ArticleScientific reports2019

Preoperative Prediction of Axillary Lymph Node Metastasis in Breast Cancer Using Mammography-Based Radiomics Method.

Jingbo Yang, Tao Wang, Lifeng Yang, Yubo Wang, Hongmei Li, Xiaobo Zhou, Weiling Zhao, Junchan Ren, Xiaoyong Li, Jie Tian and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jingbo YangSchool of Life Science and Technology, Xidian University, Xi'an, Shaanxi, 710071, China.
Tao WangDepartment of Radiology, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, 710068, China.
Lifeng YangSchool of Life Science and Technology, Xidian University, Xi'an, Shaanxi, 710071, China.
Yubo WangSchool of Life Science and Technology, Xidian University, Xi'an, Shaanxi, 710071, China.
Hongmei LiDepartment of Breast Diseases, Yan'an University Affiliated Hospital, Yan'an, Shaanxi, 716000, China.
Xiaobo ZhouDepartment of Radiology, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina, 27157, USA. zhouxb2015@163.com.
Weiling ZhaoDepartment of Radiology, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina, 27157, USA.
Junchan RenSchool of Life Science and Technology, Xidian University, Xi'an, Shaanxi, 710071, China.
Xiaoyong LiDepartment of Breast Diseases, Yan'an University Affiliated Hospital, Yan'an, Shaanxi, 716000, China.
Jie TianSchool of Life Science and Technology, Xidian University, Xi'an, Shaanxi, 710071, China.
Liyu HuangSchool of Life Science and Technology, Xidian University, Xi'an, Shaanxi, 710071, China. huangly@mail.xidian.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is difficult to accurately assess axillary lymph nodes metastasis and the diagnosis of axillary lymph nodes in patients with breast cancer is invasive and has low-sensitivity preoperatively. This study aims to develop a mammography-based radiomics nomogram for the preoperative prediction of ALN metastasis in patients with breast cancer. This study enrolled 147 patients with clinicopathologically confirmed breast cancer and preoperative mammography. Features were extracted from each patient's mammography images. The least absolute shrinkage and selection operator regression method was used to select features and build a signature in the primary cohort. The performance of the signature was assessed using support vector machines. We developed a nomogram by incorporating the signature with the clinicopathologic risk factors. The nomogram performance was estimated by its calibration ability in the primary and validation cohorts. The signature was consisted of 10 selected ALN-status-related features. The AUC of the signature from the primary cohort was 0.895 (95% CI, 0.887-0.909) and 0.875 (95% CI, 0.698-0.891) for the validation cohort. The C-Index of the nomogram from the primary cohort was 0.779 (95% CI, 0.752-0.793) and 0.809 (95% CI, 0.794-0.833) for the validation cohort. Our nomogram is a reliable and non-invasive tool for preoperative prediction of ALN status and can be used to optimize current treatment strategy for breast cancer patients.

Indexed as

AlgorithmsNomogramsPreoperative CareBreast NeoplasmsFemaleFollow-Up StudiesHumansLymphatic MetastasisLymph NodesMammographyMiddle AgedPrognosisRetrospective StudiesTomography, X-Ray Computed

Identifiers

PMID30872652
PMCPMC6418289

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.