Observational studyBMJ open2019
Acute kidney injury and 1-year mortality after colorectal cancer surgery: a population-based cohort study.
Observational study in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 52 citations in OpenAlex.
- Article
- Predicting acute kidney injury after radical cystectomy for muscle-invasive bladder cancer.BMC urology · 2026Article
- Colorectal Endoscopic Submucosal Dissection and Acute Kidney Injury: A Rare but Clinically Relevant Adverse Event, a Cohort Study of 1537 Patients.Endoscopy international open · 2026Article
- Development of a prediction model for acute kidney injury in critically ill patients with advanced colorectal cancer based on white blood cell-related indicators.Frontiers in oncology · 2026Article
- No increase in chronic kidney disease after postoperative acute kidney injury in gynecologic oncologic ERAS surgery.Gynecologic oncology · 2025Article
- Risk of and Mortality After Acute Kidney Injury Following Cancer Treatment: A Cohort Study.Cancer medicine · 2025Article
- Prevalence and Risk Factors of Acute Kidney Injury After Colorectal Cancer Surgery.Journal of gastrointestinal cancer · 2025Article
- Prevalence and prognostic value of baseline and post-treatment renal insufficiency in colorectal cancer patients: a large retrospective cohort study of 10,581 patients in Shanghai, China (2019-2023).Frontiers in medicine · 2025Article
- Risk factors and outcomes of renal insufficiency after colectomy for diverticulitis.Techniques in coloproctology · 2024Article
- Preoperative risk factors for ileostomy-associated kidney injury in colorectal tumor surgery following ileostomy formation.International journal of colorectal disease · 2024Article
- Acute kidney injury after colorectal surgery with prophylactic ureteral stents.Surgical endoscopy · 2024Article
- Recovery of kidney function after acute kidney disease-a multi-cohort analysis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024Article
- Acute kidney injury after radical gastrectomy: incidence, risk factors, and impact on prognosis.Gastroenterology report · 2024Article
- Preoperative urine neutrophil gelatinase-associated lipocalin predicts mortality in colorectal cancer patients after laparoscopic surgery: A single-center study.Health science reports · 2023Article
- The risk of acute kidney injury in colorectal cancer survivors: an english population-based matched cohort study.BMC cancer · 2023Article
- Analysis of factors associated with postoperative acute kidney injury in patients with colorectal cancer and the development of a risk prediction model: a retrospective study.Updates in surgery · 2023Article
- Acute kidney injury after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in patients with advanced ovarian cancer.Frontiers in oncology · 2023Article
- Causes of death among early-onset colorectal cancer population in the United States: a large population-based study.Frontiers in oncology · 2023Article
- Chronic Kidney Disease Prevalence in Patients with Colorectal Cancer Undergoing Surgery.Diagnostics (Basel, Switzerland) · 2022Article
- Acute Kidney Injury and 3-Year Mortality in Elderly Patients After Non-cardiac Surgery.Frontiers in medicine · 2022Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesAcute kidney injury (AKI) is a frequent postoperative complication, but the mortality impact within different postoperative time frames and severities of AKI are poorly understood. We examined the occurrence of postoperative AKI among colorectal cancer (CRC) surgery patients and the impact of AKI on mortality during 1 year after surgery.
designObservational cohort study. We defined the exposure, AKI, as a 50% increase in plasma creatinine or initiation of renal replacement therapy within 7 days after surgery or an absolute increase in creatinine of 26 µmol/L within 48 hours.
settingPopulation-based Danish medical databases.
participantsA total of 6580 patients undergoing CRC surgery in Northern Denmark during 2005-2011 were included from the Danish Colorectal Cancer Group database. OUTCOMES MEASURE: Occurrence of AKI and 8-30, 31-90 and 91-365 days mortality in patient with or without AKI.
resultsAKI occurred in 1337 patients (20.3%) of the 6580 patients who underwent CRC surgery. Among patients with AKI, 8-30, 31-90 and 91-365 days mortality rates were 10.1% (95% CI 8.6% to 11.9%), 7.8% (95% CI 6.4% to 9.5%) and 12.0% (95% CI 10.3% to 14.2%), respectively. Compared with patients without AKI, AKI was associated with increased 8-30 days mortality (adjusted HR (aHR)=4.01,95% CI 3.11 to 5.17) and 31-90 days mortality (aHR 2.08,95% CI 1.60 to 2.69), while 91-365 days aHR was 1.12 (95% CI 0.89 to 1.41). We observed no major differences in stratified analyses.
conclusionsAKI after surgery for CRC is a frequent postoperative complication associated with a substantially increased 90-day mortality. AKI should be considered a potential target for reducing 90-day mortality.
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