Evidence map›Paper›PMID 30872543›Full record

ArticleBMJ open2019

Validated methods to identify patients with asthma-COPD overlap in healthcare databases: a systematic review protocol.

Joseph Emil Amegadzie, Oluwatosin Badejo, John-Michael Gamble, Mark Wright, Jamie Farrell, Brooke Jackson, Kirin Sultana, Maimoona Hashmi, Zhiwei Gao

Abstract readValidation Study
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Joseph Emil AmegadzieDepartment of Medicine, Memorial University of Newfoundland, St. John's, Newfoundland and Labrador, Canada.ORCID 0000-0002-0459-7241
Oluwatosin BadejoDepartment of Medicine, Memorial University of Newfoundland, St. John's, Newfoundland and Labrador, Canada.
John-Michael GambleDepartment of Pharmacy, University of Waterloo, Kitchener, Ontario, Canada.ORCID 0000-0001-6891-8721
Mark WrightClinical Practice Research Datalink (CPRD), Medicines and Healthcare Products Regulatory Agency, London, UK.
Jamie FarrellDepartment of Medicine, Memorial University of Newfoundland, St. John's, Newfoundland and Labrador, Canada.
Brooke JacksonClinical Practice Research Datalink (CPRD), Medicines and Healthcare Products Regulatory Agency, London, UK.
Kirin SultanaClinical Practice Research Datalink (CPRD), Medicines and Healthcare Products Regulatory Agency, London, UK.
Maimoona HashmiClinical Practice Research Datalink (CPRD), Medicines and Healthcare Products Regulatory Agency, London, UK.
Zhiwei GaoDepartment of Medicine, Memorial University of Newfoundland, St. John's, Newfoundland and Labrador, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAsthma-chronic obstructive pulmonary disease (COPD) overlap (ACO) is characterised by patients presenting symptoms of both asthma and COPD. Many efforts have been made to validate different methods of identifying asthma-COPD overlap cases based on symptoms, spirometry and medical history in epidemiological studies using healthcare databases. There are various coding algorithm strategies that can be used and selection depends on targeted validation. The primary objectives of this systematic review are to identify validated methods (or algorithms) that identify patients with ACO from healthcare databases and summarise the reported validity measures of these methods.

methodsMEDLINE, EMBASE databases and the Web of Science will be systematically searched by using appropriate search strategies that are able to identify studies containing validated codes and algorithms for the diagnosis of ACO in healthcare databases published, in English, before October 2018. For each selected study, we require the presence of at least one test measure (eg, sensitivity, specificity etc). We will also include studies, in which the validated algorithm is compared with an external reference standard such as questionnaires completed by patients or physicians, medical charts review, manual review or an independent second database. For all selected studies, a uniform table will be created to summarise the following vital information: name of author, publication year, country, data source, population, clinical outcome, algorithms, reference standard method of validation and characteristics of the test measure used to determine validity. PROSPERO REGISTRATION NUMBER: CRD42018087472.

Indexed as

AlgorithmsAsthmaDatabases, FactualPulmonary Disease, Chronic ObstructiveSystematic Reviews as TopicDisease ManagementHumansSpirometryasthma-COPD overlapcoding algorithmshealthcare databasevalidation

Identifiers

PMID30872543
PMCPMC6429878

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.