Evidence map›Paper›PMID 30872471›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Glycoconjugate vaccine using a genetically modified O antigen induces protective antibodies to

Giuseppe Stefanetti, Nihal Okan, Avner Fink, Erica Gardner, Dennis L Kasper

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 50 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Mutation inVeterinary sciences · 2024
    Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Circulating T Cells Are Not Sufficient for Protective Immunity against VirulentJournal of immunology (Baltimore, Md. : 1950) · 2022
    Article
  15. Review
  16. The bacterial tyrosine kinase system CpsBCD governs the length of capsule polymers.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  17. Article
  18. Synthesis and delivery ofProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  19. Review
  20. Virulence ofMicroorganisms · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Giuseppe StefanettiDepartment of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.
Nihal OkanDepartment of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.
Avner FinkThe Lautenberg Center for Immunology and Cancer Research, Hebrew University-Hadassah Medical School, 91120 Jerusalem, Israel.
Erica GardnerDepartment of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.
Dennis L KasperDepartment of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115; dennis_kasper@hms.harvard.edu.ORCID 0000-0001-8808-5333
Harvard University · USHebrew University of Jerusalem · IL

Funding

Targeting bacterial cell wall biogenesis for the development of novel antimicrobU19AI109764 · NIAID · HARVARD MEDICAL SCHOOL · PI BELTZ, GERALD A · 2014 to 2018
$25.2M
Knowledge-based Vaccines Built on Paradigm Changes in Antigen PresentationR01AI089915 · NIAID · HARVARD MEDICAL SCHOOL · PI KASPER, DENNIS L. · 2011 to 2015
$2.1M
NIAID NIH HHS R01 AI089915NIAID NIH HHS U19 AI109764
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

TularemiaAnimalsBacterial VaccinesFemaleFrancisella tularensisGlycoconjugatesMiceMice, Inbred BALB CO AntigensBacterial VaccinesGlycoconjugatesO Antigensantibody affinityFrancisellaglycoconjugate vaccineintracellular pathogenO antigen

Identifiers

PMID30872471
PMCPMC6452683
OpenAlexW2922524486

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.