Evidence map›Paper›PMID 30872456›Full record

ArticleJournal of cell science2019

Multiple feedback mechanisms fine-tune Rho signaling to regulate morphogenetic outcomes.

Katy Ong, Camille Collier, Stephen DiNardo

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cell science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Generation ofmicroPublication biology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Katy OngCell and Developmental Biology Department, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19146, USA.ORCID 0000-0001-6237-3580
Camille CollierSchool of Arts and Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA.
Stephen DiNardoCell and Developmental Biology Department, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19146, USA sdinardo@pennmedicine.upenn.edu.ORCID 0000-0003-4131-5511
University of Pennsylvania · US

Funding

TRAINING PROGRAM IN CELL AND MOLECULAR BIOLOGYT32GM007229 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI BARTOLOMEI, MARISA S. · 1985 to 2023
$14.0M
Stem Cell Renewal And Differentiation in SpermatogenesisR01GM060804 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI DINARDO, STEPHEN FRANCIS · 1999 to 2019
$6.7M
Graduate Training in Developmental BiologyT32HD083185 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI Michael Granato, Foteini Mourkioti · 2015 to 2026
$4.0M
PATTERNING: THE CELL BIOLOGY OF DEVELOPMENTAL SIGNALINGR01GM045747 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI DINARDO, STEPHEN FRANCIS · 1992 to 2013
$3.6M
Spatiotemporal regulation of mechanical networks drives coordinated epithelial cell shape changesF31GM117708 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI ONG, KATY · 2016 to 2017
$74k
NICHD NIH HHS T32 HD083185NIGMS NIH HHS F31 GM117708NIGMS NIH HHS R01 GM045747NIGMS NIH HHS R01 GM060804NIGMS NIH HHS T32 GM007229
6 · The paper itself

Abstract

Rho signaling is a conserved mechanism for generating forces through activation of contractile actomyosin. How this pathway can produce different cell morphologies is poorly understood. In the

Indexed as

MorphogenesisSignal TransductionActin CytoskeletonActinsActomyosinAnimalsCell PolarityDrosophilaDrosophila ProteinsEmbryonic DevelopmentEpitheliumMyosin Type IIrho GTP-Binding ProteinsActinsActomyosinDrosophila ProteinsMyosin Type IIrho GTP-Binding ProteinsActomyosin contractilityDevelopmental mechanicsDrosophila melanogasterEpithelial morphogenesisNon-muscle Myosin-IIRho signalingZipper

Identifiers

PMID30872456
PMCPMC6503953
OpenAlexW2921678233

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.