Evidence map›Paper›PMID 30872407›Full record

ArticleBioscience reports2019

MicroRNA-26a reduces synovial inflammation and cartilage injury in osteoarthritis of knee joints through impairing the NF-κB signaling pathway.

Zhi Zhao, Xiu-Song Dai, Zhi-Yan Wang, Zheng-Qi Bao, Jian-Zhong Guan

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in Bioscience reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
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  14. Article
  15. MicroRNA-34a-5p Promotes Joint Destruction During Osteoarthritis.Arthritis & rheumatology (Hoboken, N.J.) · 2021
    Article
  16. Crosstalk Among circRNA/lncRNA, miRNA, and mRNA in Osteoarthritis.Frontiers in cell and developmental biology · 2021
    Review
  17. Review
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  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Zhi ZhaoDepartment of Orthopedics, The First Affiliated Hospital of Bengbu Medical College, Bengbu 233004, Anhui Province, P.R. China.
Xiu-Song DaiDepartment of Orthopedics, The First Affiliated Hospital of Bengbu Medical College, Bengbu 233004, Anhui Province, P.R. China.
Zhi-Yan WangDepartment of Orthopedics, The First Affiliated Hospital of Bengbu Medical College, Bengbu 233004, Anhui Province, P.R. China.
Zheng-Qi BaoDepartment of Orthopedics, The First Affiliated Hospital of Bengbu Medical College, Bengbu 233004, Anhui Province, P.R. China.
Jian-Zhong GuanDepartment of Orthopedics, The First Affiliated Hospital of Bengbu Medical College, Bengbu 233004, Anhui Province, P.R. China guanjianzhong0531@163.com.ORCID 0000-0002-5859-7650
First Affiliated Hospital of Bengbu Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsFemaleInflammationMaleMicroRNAsNF-kappa BOsteoarthritis, KneeRatsRats, Sprague-DawleySignal TransductionSynovial MembraneSynoviocytesMicroRNAsMIRN26 microRNA, ratNF-kappa BCartilage injuryInflammatory injuryMicroRNA-26aNF-κB signaling pathwayOsteoarthritisSynovial inflammation

Identifiers

PMID30872407
PMCPMC6454017
OpenAlexW2922060164

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.