ArticleInternational journal of environmental research and public health2019
Race-, Age-, and Anatomic Site-Specific Gender Differences in Cutaneous Melanoma Suggest Differential Mechanisms of Early- and Late-Onset Melanoma.
Article in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 58 citations in OpenAlex.
- Global assessment of surface ultraviolet radiation and malignant skin melanoma incidence from 1990 to 2021.Scientific reports · 2025Article
- [Disease burden and trend of melanoma among middle-aged and elderly population in China from 1990 to 2020, and prediction for 2022 to 2035].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2025Article
- Melanoma in a Colombian population: a survival study.Melanoma management · 2024Article
- A retrospective single-institute study reveals a vertical gradient of the density of cutaneous melanoma from head to toe.Skin health and disease · 2024Article
- Incidence and mortality trends of primary cutaneous melanoma: A 50-year Rochester Epidemiologic Project study.JAAD international · 2024Article
- Radiomic and deep learning analysis of dermoscopic images for skin lesion pattern decoding.Scientific reports · 2024Article
- Melanoma in Pregnancy-Diagnosis, Treatment, and Consequences for Fetal Development and the Maintenance of Pregnancy.Cancers · 2024Review
- A Narrative Review of Current Knowledge on Cutaneous Melanoma.Clinics and practice · 2024Review
- The role of immune checkpoint inhibitors in clinical practice: an analysis of the treatment patterns, survival and toxicity rates by sex.Journal of cancer research and clinical oncology · 2023Article
- Melanoma survival by age group: Population-based disparities for adolescent and young adult patients by stage, tumor thickness, and insurance type.Journal of the American Academy of Dermatology · 2023Article
- Anatomic Region of Cutaneous Melanoma Impacts Survival and Clinical Outcomes: A Population-Based Analysis.Cancers · 2023Article
- Characteristics, Treatments, and Survival of Uveal Melanoma: A Comparison between Chinese and American Cohorts.Cancers · 2022Article
- Cutaneous Melanoma in Alpine Population: Incidence Trends and Clinicopathological Profile.Current oncology (Toronto, Ont.) · 2022Article
- Ambient UVR and Environmental Arsenic Exposure in Relation to Cutaneous Melanoma in Iowa.International journal of environmental research and public health · 2022Article
- Towards gender equity in artificial intelligence and machine learning applications in dermatology.Journal of the American Medical Informatics Association : JAMIA · 2022Article
- Changing epidemiology and age-specific incidence of cutaneous malignant melanoma in Lithuania: an analysis of national cancer registration data by gender and anatomical site, 1991-2015.Contemporary oncology (Poznan, Poland) · 2022Article
- Analysis of Demographics and Outcomes of Surgical Resection in the Central Nervous System of Patients With Metastatic Melanoma.World journal of oncology · 2021Article
- Sex disparity in skin carcinogenesis and potential influence of sex hormones.Skin health and disease · 2021Review
- Review
- Effect of hypoxia factors gene silencing on ROS production and metabolic status of A375 malignant melanoma cells.Scientific reports · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
In order to explore melanoma risk factors through gender-, age-, race-, and site-specific incidence rates, malignant melanoma cases from the Caucasian whites and non-whites were retrieved from the US SEER database. Age-standardized, age-, and site-specific tumor rates were calculated. All races and both genders showed positive annual average percentage changes (AAPCs) over the years, but AAPCs varied at different body sites, with men's trunk exhibiting the fastest increase. Non-whites were diagnosed at a significantly younger age than whites and showed a trend towards fewer gender differences in the age of diagnosis. However, non-whites and whites showed a similar pattern of age-specific gender differences in the incidence rate ratios. A consistent spiked difference (female vs. male, incidence rate ratio (IRR) >2) was observed at or near the age of 20⁻24 in all race groups and at all body sites. The highest female vs. male IRR was found in the hip and lower extremities, and the lowest IRR was found in the head and neck region in all races. These race-, gender-, and site-dependent differences suggest that age-associated cumulative sun exposure weighs significantly more in late-onset melanomas, while genetics and/or pathophysiological factors make important contributions to early-onset melanomas.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.