Evidence map›Paper›PMID 30871199›Full record

ArticleAntioxidants (Basel, Switzerland)2019

Hydroxycobalamin Reveals the Involvement of Hydrogen Sulfide in the Hypoxic Responses of Rat Carotid Body Chemoreceptor Cells.

Teresa Gallego-Martin, Jesus Prieto-Lloret, Philip I Aaronson, Asuncion Rocher, Ana Obeso

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Teresa Gallego-MartinDepartamento de Bioquímica y Biología Molecular y Fisiología. Facultad de Medicina. Universidad de Valladolid. Instituto de Biología y Genética Molecular-CSIC, 47005 Valladolid, Spain. tgallego@ibgm.uva.es.
Jesus Prieto-LloretDepartamento de Bioquímica y Biología Molecular y Fisiología. Facultad de Medicina. Universidad de Valladolid. Instituto de Biología y Genética Molecular-CSIC, 47005 Valladolid, Spain. jesus.prieto@uva.es.ORCID 0000-0002-5281-0211
Philip I AaronsonDepartment of Inflammation Biology, School of Immunology and Microbial Sciences, Faculty of Life Sciences and Medicine, King's College, London SE1 1UL, UK. philip.aaronson@kcl.ac.uk.ORCID 0000-0003-1086-1202
Asuncion RocherDepartamento de Bioquímica y Biología Molecular y Fisiología. Facultad de Medicina. Universidad de Valladolid. Instituto de Biología y Genética Molecular-CSIC, 47005 Valladolid, Spain. rocher@ibgm.uva.es.
Ana ObesoDepartamento de Bioquímica y Biología Molecular y Fisiología. Facultad de Medicina. Universidad de Valladolid. Instituto de Biología y Genética Molecular-CSIC, 47005 Valladolid, Spain. aobeso@ibgm.uva.es.ORCID 0000-0003-3197-1697
Universidad de Valladolid · ESKing's College London · GB

Funding

CIBERES-ISCIII CIBER CB06/06/0050Junta de Castilla y Leon VA106G18MINECO/FEDER-DGICYT BFU2015-70616-R
6 · The paper itself

Abstract

Carotid body (CB) chemoreceptor cells sense arterial blood PO₂, generating a neurosecretory response proportional to the intensity of hypoxia. Hydrogen sulfide (H₂S) is a physiological gaseous messenger that is proposed to act as an oxygen sensor in CBs, although this concept remains controversial. In the present study we have used the H₂S scavenger and vitamin B

Indexed as

carotid bodyhydrogen sulfidehydroxycobalaminhypoxiaoxygen sensing

Identifiers

PMID30871199
PMCPMC6466535
OpenAlexW2921322873

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.