Evidence map›Paper›PMID 30871183›Full record

ArticleNutrients2019

Intestinal Anti-Inflammatory Effect of a Peptide Derived from Gastrointestinal Digestion of Buffalo (

Gian Carlo Tenore, Ester Pagano, Stefania Lama, Daniela Vanacore, Salvatore Di Maro, Maria Maisto, Raffaele Capasso, Francesco Merlino, Francesca Borrelli, Paola Stiuso and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Review
  3. Macronutrients as Regulators of Intestinal Epithelial Permeability: Where Do We Stand?Comprehensive reviews in food science and food safety · 2025
    Review
  4. Article
  5. Review
  6. Sex hormone deprivation abolishes sex-specific differences in murine colon inflammation and related lipid mediator production.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Gian Carlo TenoreDepartment of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via D. Montesano 49, 80131 Naples, Italy. giancarlo.tenore@unina.it.ORCID 0000-0002-0251-9936
Ester PaganoDepartment of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via D. Montesano 49, 80131 Naples, Italy. ester.pagano@unina.it.
Stefania LamaDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", Via De Crecchio 7, 80138 Naples, Italy. stefania.lama@unicampania.it.
Daniela VanacoreDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", Via De Crecchio 7, 80138 Naples, Italy. daniela.vanacore@unicampania.it.
Salvatore Di MaroDiSTABiF, Università degli Studi della Campania "Luigi Vanvitelli", via Vivaldi 43, 81100 Caserta, Italy. salvatore.dimaro@unicampania.it.ORCID 0000-0002-9286-4433
Maria MaistoDepartment of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via D. Montesano 49, 80131 Naples, Italy. maria.maisto@unina.it.ORCID 0000-0002-0340-2254
Raffaele CapassoDepartment of Agricultural Sciences, University of Naples Federico II, 80055 Portici, Italy. raffaele.capasso@unina.it.
Francesco MerlinoDepartment of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via D. Montesano 49, 80131 Naples, Italy. francesco.merlino@unina.it.ORCID 0000-0002-9607-229X
Francesca BorrelliDepartment of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via D. Montesano 49, 80131 Naples, Italy. franborr@unina.it.ORCID 0000-0002-2695-3294
Paola StiusoDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", Via De Crecchio 7, 80138 Naples, Italy. paola.stiuso@unicampania.it.
Ettore NovellinoDepartment of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via D. Montesano 49, 80131 Naples, Italy. ettore.novellino@unina.it.
University of Naples Federico II · ITUniversity of Campania "Luigi Vanvitelli" · ITFederico II University Hospital · IT

Funding

Regione Campania Eicure and Combattere la resistenza tumorale: piattaforma integrata multidisciplinare per un approccio tecnologico innovativo alle oncoterapie- CAMPANIA ONCO TERAPIE
6 · The paper itself

Abstract

Under physiological conditions, the small intestine represents a barrier against harmful antigens and pathogens. Maintaining of the intestinal barrier depends largely on cell⁻cell interactions (adherent-junctions) and cell⁻matrix interactions (tight-junctions). Inflammatory bowel disease is characterized by chronic inflammation, which induces a destructuring of the architecture junctional epithelial proteins with consequent rupture of the intestinal barrier. Recently, a peptide identified by

Indexed as

AnimalsAnti-Inflammatory AgentsBenzenesulfonatesBuffaloesCaco-2 CellsCheeseColitisFood AnalysisHumansInflammationMaleMiceMice, Inbred ICRPeptidesAnti-Inflammatory AgentsBenzenesulfonatesdinitrobenzenesulfonic acidPeptidesbioactive peptidesepithelial adherens junctionsinflammatory bowel diseaseintestinal inflammation

Identifiers

PMID30871183
PMCPMC6471453
OpenAlexW2921199942

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.