Evidence map›Paper›PMID 30871147›Full record

ArticleMolecules (Basel, Switzerland)2019

Synthesis of Thymidine Phosphorylase Inhibitor Based on Quinoxaline Derivatives and Their Molecular Docking Study.

Noor Barak Almandil, Muhammad Taha, Rai Khalid Farooq, Amani Alhibshi, Mohamed Ibrahim, El Hassane Anouar, Mohammed Gollapalli, Fazal Rahim, Muhammad Nawaz, Syed Adnan Ali Shah and 2 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 3 countries.

Noor Barak AlmandilDepartment of Clinical Pharmacy, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia. nbalmandil@iau.edu.sa.
Muhammad TahaDepartment of Clinical Pharmacy, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia. mtaha@iau.edu.sa.
Rai Khalid FarooqDepartment of Neuroscience Research, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia. rkfarooq@iau.edu.sa.
Amani AlhibshiDepartment of Neuroscience Research, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia. ahalhibshi@iau.edu.sa.
Mohamed IbrahimDepartment of Clinical Pharmacy, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia. msmibrahim@iau.edu.sa.ORCID 0000-0001-9477-1284
El Hassane AnouarDepartment of Chemistry, College of Sciences and Humanities, Prince Sattam bin Abdulaziz University, P.O. Box 83, Al-Kharij 11942, Saudi Arabia. e.anouar@psau.edu.sa.
Mohammed GollapalliCollege of Computer Science & Information Technology (CCSIT) Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia. magollapalli@iau.edu.sa.
Fazal RahimDepartment of Chemistry, Hazara University, Mansehra 21300, Khyber Pakhtunkhwa, Pakistan. fazalstar@gmail.com.
Muhammad NawazDepartment of Nano-Medicine Research, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia. mnnmuhammad@iau.edu.sa.
Syed Adnan Ali ShahFaculty of Pharmacy, Universiti Teknologi MARA Puncak Alam Campus, 42300 Bandar Puncak Alam, Selangor D.E., Malaysia. benzene301@yahoo.com.ORCID 0000-0002-8142-5013
Qamar Uddin AhmedDepartment of Pharmaceutical Chemistry, Kulliyyah of Pharmacy, International Islamic University Malaysia, 25200 Kuantan Pahang DM, Malaysia. quahmed@iium.edu.my.ORCID 0000-0003-0565-3222
Zainul Amiruddin ZakariaDepartment of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia. zaz@upm.edu.my.ORCID 0000-0001-5525-7821
Imam Abdulrahman Bin Faisal University · SAHazara University · PKInternational Islamic University Malaysia · MYPrince Sattam Bin Abdulaziz University · SAUniversiti Putra Malaysia · MYUniversiti Teknologi MARA · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have synthesized quinoxaline analogs (

Indexed as

Dose-Response Relationship, DrugEnzyme InhibitorsInhibitory Concentration 50Molecular Docking SimulationMolecular StructureProton Magnetic Resonance SpectroscopyQuinoxalinesStructure-Activity RelationshipThymidine PhosphorylaseEnzyme InhibitorsQuinoxalinesThymidine Phosphorylasemolecular dockingquinoxaline analogssynthesisthymidine phosphorylase inhibition

Identifiers

PMID30871147
PMCPMC6471342
OpenAlexW2909884322

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.