Evidence map›Paper›PMID 30871143›Full record

Observational studyInternational journal of environmental research and public health2019

Evaluation of DNA Methylation Changes and Micronuclei in Workers Exposed to a Construction Environment.

Isana R Silva, Manoela C A S Ramos, Lídia M R B Arantes, André V H Lengert, Marco A Oliveira, Fernanda P Cury, Guilherme Martins Pereira, Aldenor G Santos, Fernando Barbosa, Pérola C Vasconcellos and 3 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Isana R SilvaMolecular Oncology Research Center, Barretos Cancer Hospital, Barretos 14784-400, São Paulo, Brazil. isanateclab@hotmail.com.
Manoela C A S RamosMolecular Oncology Research Center, Barretos Cancer Hospital, Barretos 14784-400, São Paulo, Brazil. manoelaaguena@gmail.com.
Lídia M R B ArantesMolecular Oncology Research Center, Barretos Cancer Hospital, Barretos 14784-400, São Paulo, Brazil. lirebolho@hotmail.com.ORCID 0000-0001-8230-1218
André V H LengertMolecular Oncology Research Center, Barretos Cancer Hospital, Barretos 14784-400, São Paulo, Brazil. ahlengert@gmail.com.
Marco A OliveiraCenter for Research Support (NAP), Barretos Cancer Hospital, Barretos 14784-400, São Paulo, Brazil. marco.bioestatistica@hcancerbarretos.com.br.
Fernanda P CuryMolecular Oncology Research Center, Barretos Cancer Hospital, Barretos 14784-400, São Paulo, Brazil. fernandacury_7@hotmail.com.
Guilherme Martins PereiraInstituto de Química-USP, São Paulo 05508-000, Brazil. martinspereira2@hotmail.com.
Aldenor G SantosInstituto de Química-UFBA, Salvador 40170-115, Bahia, Brazil. gomes_aldo@hotmail.com.
Fernando BarbosaSchool of Pharmaceutical Sciences, University of São Paulo, Ribeirão Preto 14040-903, São Paulo, Brazil. fbarbosa@fcfrp.usp.br.ORCID 0000-0002-2498-0619
Pérola C VasconcellosInstituto de Química-USP, São Paulo 05508-000, Brazil. perola@iq.usp.br.
Cyrille CueninEpigenetics Group, International Agency for Research on Cancer (IARC), 150 Cours Albert-Thomas, 69008 Lyon, France. cueninc@iarc.fr.
Zdenko HercegEpigenetics Group, International Agency for Research on Cancer (IARC), 150 Cours Albert-Thomas, 69008 Lyon, France. HercegZ@iarc.fr.ORCID 0000-0003-4109-3154
Henrique C S SilveiraMolecular Oncology Research Center, Barretos Cancer Hospital, Barretos 14784-400, São Paulo, Brazil. henriquecssilveira@gmail.com.
Hospital de Câncer de Barretos · BRCentre international de recherche sur le cancer · FRInstituto de Botânica · BRUniversidade de São Paulo · BR

Funding

World Health Organization 001
6 · The paper itself

Abstract

Methylation levels in tumor-suppressor genes and repetitive sequences have previously been used to study the relationship between environmental air pollution and epigenetic changes related to cancer. In this study, we measured the methylation profiles of the promoter regions

Indexed as

DNA MethylationMicronucleus TestsAdultAir PollutantsCase-Control StudiesDNA DamageHumansMaleOccupational ExposurePolycyclic Aromatic HydrocarbonsPromoter Regions, GeneticAir PollutantsPolycyclic Aromatic Hydrocarbonsconstruction workersDNA methylationmetalsmicronucleipolycyclic aromatic hydrocarbons

Identifiers

PMID30871143
PMCPMC6466300
OpenAlexW2921741689

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.