Evidence map›Paper›PMID 30871132›Full record

ReviewInternational journal of molecular sciences2019

Thinking Outside the Bug: Molecular Targets and Strategies to Overcome Antibiotic Resistance.

Ana Monserrat-Martinez, Yann Gambin, Emma Sierecki

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
4.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 108 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Challenges of Carbapenem-ResistantAntibiotics (Basel, Switzerland) · 2025
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Editorial: Synergistic combinatorial treatments to overcome antibiotic resistance.Frontiers in cellular and infection microbiology · 2024
    Article
  14. Profile and Predictors of Infection Following Anti-thymocyte Globulin or Anti-lymphocyte Globulin with Cyclosporine in Aplastic Anemia.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2023
    Article
  15. Article
  16. ModifiedFrontiers in molecular biosciences · 2023
    Article
  17. Review
  18. Review
  19. Hetero-Multivalent Targeted Liposomal Drug Delivery to TreatACS applied materials & interfaces · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Ana Monserrat-MartinezEuropean Molecular Biology Laboratory Australia (EMBL Australia) Node in Single Molecule Science, Sydney, NSW 2031, Australia. a.monserrat-martinez@unsw.edu.au.
Yann GambinEuropean Molecular Biology Laboratory Australia (EMBL Australia) Node in Single Molecule Science, Sydney, NSW 2031, Australia. y.gambin@unsw.edu.au.
Emma SiereckiEuropean Molecular Biology Laboratory Australia (EMBL Australia) Node in Single Molecule Science, Sydney, NSW 2031, Australia. e.sierecki@unsw.edu.au.
EMBL Australia · AUUNSW Sydney · AU

Funding

National Health and Medical Research Council APP1108859
6 · The paper itself

Abstract

Since their discovery in the early 20th century, antibiotics have been used as the primary weapon against bacterial infections. Due to their prophylactic effect, they are also used as part of the cocktail of drugs given to treat complex diseases such as cancer or during surgery, in order to prevent infection. This has resulted in a decrease of mortality from infectious diseases and an increase in life expectancy in the last 100 years. However, as a consequence of administering antibiotics broadly to the population and sometimes misusing them, antibiotic-resistant bacteria have appeared. The emergence of resistant strains is a global health threat to humanity. Highly-resistant bacteria like

Indexed as

AnimalsAnti-Bacterial AgentsDrug Resistance, MicrobialEnterococcus faeciumGram-Positive Bacterial InfectionsHumansMethicillin-Resistant Staphylococcus aureusMolecular Targeted TherapyStaphylococcal InfectionsAnti-Bacterial Agentsantibiotic resistanceantimicrobial peptides and proteinsbacterial effectorshost–pathogen interactionsprotein–protein interactions

Identifiers

PMID30871132
PMCPMC6470534
OpenAlexW2922073122

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.