Evidence map›Paper›PMID 30871041›Full record

ArticlePharmaceutics2019

Contribution of Molecular Structure to Self-Assembling and Biological Properties of Bifunctional Lipid-Like 4-(

Martins Rucins, Pavels Dimitrijevs, Klavs Pajuste, Oksana Petrichenko, Ludmila Jackevica, Anita Gulbe, Signe Kibilda, Krisjanis Smits, Mara Plotniece, Dace Tirzite and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Selected strategies to fight pathogenic bacteria.Journal of enzyme inhibition and medicinal chemistry · 2023
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Martins RucinsLatvian Institute of Organic Synthesis, Aizkraukles str. 21, Riga LV-1006, Latvia. rucins@osi.lv.
Pavels DimitrijevsLatvian Institute of Organic Synthesis, Aizkraukles str. 21, Riga LV-1006, Latvia. p.dimitrijevs@osi.lv.
Klavs PajusteLatvian Institute of Organic Synthesis, Aizkraukles str. 21, Riga LV-1006, Latvia. klavs.pajuste@osi.lv.
Oksana PetrichenkoLatvian Institute of Organic Synthesis, Aizkraukles str. 21, Riga LV-1006, Latvia. oksana.petricenko@lu.lv.
Ludmila JackevicaLatvian Institute of Organic Synthesis, Aizkraukles str. 21, Riga LV-1006, Latvia. ludmila@farm.osi.lv.
Anita GulbeLatvian Institute of Organic Synthesis, Aizkraukles str. 21, Riga LV-1006, Latvia. anita.gulbe@farm.osi.lv.
Signe KibildaJSC Grindex, Krustpils str 53, Riga LV-1057, Latvia. signe.kibilda@grindeks.lv.
Krisjanis SmitsInstitute of Solid State Physics, University of Latvia, Kengaraga str. 8, Riga LV-1063, Latvia. smits@cfi.lu.lv.
Mara PlotnieceDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Riga Stradiņš University, Dzirciema str. 16, Riga LV-1007, Latvia. mara.plotniece@rsu.lv.
Dace TirziteLatvian Institute of Organic Synthesis, Aizkraukles str. 21, Riga LV-1006, Latvia. tirzite@latnet.lv.
Karlis PajusteLatvian Institute of Organic Synthesis, Aizkraukles str. 21, Riga LV-1006, Latvia. kpajuste@osi.lv.
Arkadij SobolevLatvian Institute of Organic Synthesis, Aizkraukles str. 21, Riga LV-1006, Latvia. arkady@osi.lv.ORCID 0000-0002-5517-1240
Janis LiepinsInstitute of Microbiology and Biotechnology, University of Latvia, Jelgavas str. 1, Riga LV-1004, Latvia. janis.liepins@lu.lv.ORCID 0000-0001-7778-5561
Ilona DomrachevaLatvian Institute of Organic Synthesis, Aizkraukles str. 21, Riga LV-1006, Latvia. ilona@farm.osi.lv.
Aiva PlotnieceLatvian Institute of Organic Synthesis, Aizkraukles str. 21, Riga LV-1006, Latvia. aiva@osi.lv.ORCID 0000-0003-2187-5693
Latvijas Organiskās Sintēzes Institūts · LVUniversity of Latvia · LVRiga Stradiņš University · LV

Funding

EuroNanoMed-II ES RTD/2017/31
6 · The paper itself

Abstract

The design of nanoparticle delivery materials possessing biological activities is an attractive strategy for the development of various therapies. In this study, 11 cationic amphiphilic 4-(

Indexed as

cytotoxicityDLSnanoparticlesphospholipid bindingpyridinium and propargyl moietiesself-assembling propertiessynthetic lipidsTEMtoxicity on microorganisms

Identifiers

PMID30871041
PMCPMC6470589
OpenAlexW2922022234

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.