Evidence map›Paper›PMID 30871021›Full record

ReviewInternational journal of molecular sciences2019

The Role of Curcumin in the Modulation of Ageing.

Anna Bielak-Zmijewska, Wioleta Grabowska, Agata Ciolko, Agnieszka Bojko, Grażyna Mosieniak, Łukasz Bijoch, Ewa Sikora

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 1 synthesis or guideline pooled it, 135 citations in OpenAlex.

  1. Pooled it
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  14. Efficacy ofCurrent issues in molecular biology · 2024
    Article
  15. Review
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  18. Genus Curcuma: chemical and ethnopharmacological role in aging process.BMC complementary medicine and therapies · 2024
    Review
  19. Furofuranoid-Type Lignans and Related Phenolics fromPlants (Basel, Switzerland) · 2024
    Article
  20. Review

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Anna Bielak-ZmijewskaNencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur St., 02-093 Warsaw, Poland. a.bielak@nencki.gov.pl.ORCID 0000-0002-6330-4867
Wioleta GrabowskaNencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur St., 02-093 Warsaw, Poland. w.grabowska@nencki.gov.pl.
Agata CiolkoNencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur St., 02-093 Warsaw, Poland. a.ciolko@nencki.gov.pl.
Agnieszka BojkoNencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur St., 02-093 Warsaw, Poland. a.bojko@nencki.gov.pl.ORCID 0000-0002-8680-3300
Grażyna MosieniakNencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur St., 02-093 Warsaw, Poland. g.mosieniak@nencki.gov.pl.
Łukasz BijochNencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur St., 02-093 Warsaw, Poland. l.bijoch@nencki.gov.pl.ORCID 0000-0002-7885-3674
Ewa SikoraNencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur St., 02-093 Warsaw, Poland. e.sikora@nencki.gov.pl.ORCID 0000-0002-1111-1748
Instytut Biologii Doświadczalnej im. Marcelego Nenckiego · PL

Funding

Narodowe Centrum Nauki UMO-2011/01/B/NZ3/02137Narodowe Centrum Nauki UMO-2014/15/B/NZ3/01150Narodowe Centrum Nauki UMO-2015/17/B/NZ3/03531Narodowe Centrum Nauki UMO-2016/21/B/NZ3/00370
6 · The paper itself

Abstract

It is believed that postponing ageing is more effective and less expensive than the treatment of particular age-related diseases. Compounds which could delay symptoms of ageing, especially natural products present in a daily diet, are intensively studied. One of them is curcumin. It causes the elongation of the lifespan of model organisms, alleviates ageing symptoms and postpones the progression of age-related diseases in which cellular senescence is directly involved. It has been demonstrated that the elimination of senescent cells significantly improves the quality of life of mice. There is a continuous search for compounds, named senolytic drugs, that selectively eliminate senescent cells from organisms. In this paper, we endeavor to review the current knowledge about the anti-ageing role of curcumin and discuss its senolytic potential.

Indexed as

AgingAnimalsCellular SenescenceCurcuminHumansLongevityQuality of LifeCurcuminageinganti-cancerautophagymicrobiotasenescencesenolytics

Identifiers

PMID30871021
PMCPMC6429134
OpenAlexW2921909140

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.