Evidence map›Paper›PMID 30871010›Full record

ArticlePharmaceuticals (Basel, Switzerland)2019

In Silico Study to Identify New Antituberculosis Molecules from Natural Sources by Hierarchical Virtual Screening and Molecular Dynamics Simulations.

Vinícius de S Pinto, Janay S C Araújo, Rai C Silva, Glauber V da Costa, Jorddy N Cruz, Moysés F De A Neto, Joaquín M Campos, Cleydson B R Santos, Franco H A Leite, Manoelito C S Junior

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  11. Studies on the Phytochemical Profile ofInternational journal of molecular sciences · 2022
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  13. Identification of Potential Insect Growth Inhibitor againstInternational journal of molecular sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Vinícius de S PintoGraduate Program in Biotechnology, State University of Feira de Santana, 44036-900 Feira de Santana, BA, Brazil. viniciuspintto@gmail.com.
Janay S C AraújoGraduate Program in Biotechnology, State University of Feira de Santana, 44036-900 Feira de Santana, BA, Brazil. janay@hotmail.com.br.
Rai C SilvaGraduate Program in Chemistry, Faculty of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, 14040-903 Ribeirão Preto, São Paulo, Brazil. raics@usp.br.
Glauber V da CostaLaboratory of Modeling and Computational Chemistry, Department of Biological and Health Sciences, Federal University of Amapá, 68902-280 Macapá, AP, Brazil. vilhenac@hotmail.com.
Jorddy N CruzLaboratory of Preparation and Computation of Nanomaterials, Federal University of Pará, 66075-110 Belém, PA, Brazil. jorddynevescruz@gmail.com.ORCID 0000-0003-0529-3714
Moysés F De A NetoLaboratory of Molecular Modeling, State University of Feira de Santana, 44036-900 Feira de Santana, BA, Brazil. moysesfagundes@gmail.com.
Joaquín M CamposDepartment of Pharmaceutical and Organic Chemistry, Faculty of Pharmacy, University of Granada, 18071 Granada, Spain. jmcampos@ugr.es.ORCID 0000-0002-9035-8123
Cleydson B R SantosLaboratory of Modeling and Computational Chemistry, Department of Biological and Health Sciences, Federal University of Amapá, 68902-280 Macapá, AP, Brazil. breno@unifap.br.ORCID 0000-0002-0271-335X
Franco H A LeiteGraduate Program in Biotechnology, State University of Feira de Santana, 44036-900 Feira de Santana, BA, Brazil. fhenrique@uefs.br.
Manoelito C S JuniorGraduate Program in Biotechnology, State University of Feira de Santana, 44036-900 Feira de Santana, BA, Brazil. mc2500@gmail.com.ORCID 0000-0002-3271-3529

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis (TB) is an infection caused by

Indexed as

molecular dockingpharmacophore modeltuberculosisvirtual screeningβ-ketoacyl-ACP synthase

Identifiers

PMID30871010
PMCPMC6469180

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.