Evidence map›Paper›PMID 30870990›Full record

ArticleMolecules (Basel, Switzerland)2019

Differential Proteomics Reveals miR-155 as a Novel Indicator of Liver and Spleen Pathology in the Symptomatic Niemann-Pick Disease, Type C1 Mouse Model.

Melissa R Pergande, Antony Cougnoux, Rathnayake A C Rathnayake, Forbes D Porter, Stephanie M Cologna

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Melissa R PergandeDepartment of Chemistry, University of Illinois at Chicago, Chicago, IL 60607, USA. mperga2@uic.edu.
Antony CougnouxDivision of Translational Medicine, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD 20879, USA. antony.cougnoux@nih.gov.
Rathnayake A C RathnayakeDepartment of Chemistry, University of Illinois at Chicago, Chicago, IL 60607, USA. rrathn2@uic.edu.
Forbes D PorterDivision of Translational Medicine, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD 20879, USA. fdporter@mail.nih.gov.
Stephanie M ColognaDepartment of Chemistry, University of Illinois at Chicago, Chicago, IL 60607, USA. cologna@uic.edu.ORCID 0000-0002-3541-3361
University of Illinois Chicago · USEunice Kennedy Shriver National Institute of Child Health and Human Development · US

Funding

Inborn Errors of Cholesterol SynthesisZIAHD000139 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI PORTER, FORBES · 2009 to 2019
$11.7M
Clinical Investigations of Niemann-Pick Disease, type CZIAHD008824 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI PORTER, FORBES · 2009 to 2019
$5.2M
Ara Parseghian Medical Research Foundation NANational Institutes of Health IRPUniversity of Illinois at Chicago NA
6 · The paper itself

Abstract

Niemann-Pick disease, type C1 (NPC1) is a rare, autosomal recessive, lipid storage disorder caused by mutations in

Indexed as

BiomarkersAnimalsDisease Models, AnimalHemeLiverMiceMice, Inbred BALB CMicroRNAsNiemann-Pick Disease, Type CPhosphatidylinositolsProteomicsSpleenBiomarkersHemeMicroRNAsMirn155 microRNA, mousePhosphatidylinositolsAJS-ESI mass spectrometrylysosomal storage disordermiR-155Niemann-Pick type C1spleen proteomics

Identifiers

PMID30870990
PMCPMC6429457
OpenAlexW2921481438

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.