Trial reportJournal of affective disorders2019
Pilot randomized controlled trial of a Spanish-language Behavioral Activation mobile app (¡Aptívate!) for the treatment of depressive symptoms among united states Latinx adults with limited English proficiency.
Trial report in Journal of affective disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 12 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 12 syntheses or guidelines pooled it.
- Smartphone apps for mental health: systematic review of the literature and five recommendations for clinical translation.BMJ open · 2025Pooled it
- User Engagement With mHealth Interventions to Promote Treatment Adherence and Self-Management in People With Chronic Health Conditions: Systematic Review.Journal of medical Internet research · 2024Pooled it
- Race, Ethnicity, and Other Cultural Background Factors in Trials of Internet-Based Cognitive Behavioral Therapy for Depression: Systematic Review.Journal of medical Internet research · 2024Pooled it
- App-Based Interventions for Moderate to Severe Depression: A Systematic Review and Meta-Analysis.JAMA network open · 2023Pooled it
- Assessing Patient Adherence to and Engagement With Digital Interventions for Depression in Clinical Trials: Systematic Literature Review.Journal of medical Internet research · 2023Pooled it
- Efficacy of stand-alone digital mental health applications for anxiety and depression: A meta-analysis of randomized controlled trials.Journal of psychiatric research · 2023Pooled it
- Internet-Based Behavioral Activation for Depression: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2023Pooled it
- Factors Influencing Adherence to mHealth Apps for Prevention or Management of Noncommunicable Diseases: Systematic Review.Journal of medical Internet research · 2022Pooled it
- Characteristics of Mobile Health Platforms for Depression and Anxiety: Content Analysis Through a Systematic Review of the Literature and Systematic Search of Two App Stores.Journal of medical Internet research · 2022Pooled it
- The effectiveness of adapted psychological interventions for people from ethnic minority groups: A systematic review and conceptual typology.Clinical psychology review · 2021Pooled it
- Electronic Tools to Bridge the Language Gap in Health Care for People Who Have Migrated: Systematic Review.Journal of medical Internet research · 2021Pooled it
- Exploring the Role of Persuasive Design in Unguided Internet-Delivered Cognitive Behavioral Therapy for Depression and Anxiety Among Adults: Systematic Review, Meta-analysis, and Meta-regression.Journal of medical Internet research · 2021Pooled it
- Validation of the Effectiveness of a Behavioral Activation-Based Digital App for Treatment of Depressive Symptoms: A Randomized Controlled Trial.Behavioral sciences (Basel, Switzerland) · 2025Article
- Development of Powerly, unguided mobile app intervention preventing postpartum depression and anxiety & study protocol of randomized clinical trial.Internet interventions · 2025Article
- Digital Health Technology Use Among Spanish Speakers in the US: A Scoping Review.JAMA network open · 2025Article
- The EmpkinS-EKSpression Reappraisal Training Augmented With Kinesthesia in Depression: One-Armed Feasibility Study.JMIR formative research · 2025Article
- Quality of Psychiatric Care for Immigrants and People With a Non-English Language Preference: A Systematic Scoping Review.Psychiatric services (Washington, D.C.) · 2025Article
- Systematic review and meta-analysis of adverse events in clinical trials of mental health apps.NPJ digital medicine · 2024Article
- Community Health Workers as Mental Health Paraprofessionals: Protocol for a Mixed-Methods Pilot Feasibility Study.JMIR research protocols · 2024Article
- Self-Guided Mental Health Apps Targeting Racial and Ethnic Minority Groups: Scoping Review.JMIR mental health · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
backgroundTo address the need for disseminable, evidence-based depression treatment options for Latinx adults with limited English proficiency (LEP), our team developed ¡Aptívate!, a Spanish-language Behavioral Activation self-help mobile application. Primary aims of this study were to: 1) examine feasibility and uptake of ¡Aptívate! among depressed Latinx adults with LEP and 2) preliminarily examine ¡Aptívate! efficacy for depression treatment.
methodsParticipants (N = 42) with elevated depressive symptoms were randomized 2:1:1 to: 1) ¡Aptívate! (n = 22), 2) an active control Spanish-language app ("iCouch CBT"; n = 9), or 3) Treatment As Usual (i.e., no app; n = 11). Feasibility was assessed via self-reported app utilization and app analytics data. Depressive symptoms were assessed weekly for eight weeks via self report.
resultsAll ¡Aptívate! participants used the app at least once, 81.8% of participants used the app ≥8 times, and 36.4% of participants used the app ≥56 times. Weekly retention was strong: 72.7% and 50% of participants continued to use the app at one- and two-months post-enrollment, respectively. Generalized Estimating Equation models indicated a significant interaction between time and treatment, such that ¡Aptívate! participants reported significantly lower depressive symptoms over time than TAU. Depressive symptoms did not differ on average across time between the iCouch and TAU conditions, nor between iCouch and ¡Aptívate!. LIMITATIONS: Limitations include small sample size, limited follow-up, and lack of analytics data for the active control condition.
conclusionsWith further research, ¡Aptívate! may offer a feasible, efficacious approach to extend the reach of evidence-based depression treatment for Latinx adults with LEP.
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Registered trials
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