ArticleJournal of dental research2019
Association of Maternal Vitamin D Deficiency with Early Childhood Caries.
Article in Journal of dental research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 4 of them syntheses that pooled it.
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Who cites it
31 citing papers in PubMed, 4 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- Vitamin D as a candidate host susceptibility factor in sugar-driven oral dysbiosis.Frontiers in oral health · 2026Pooled it
- Association between prenatal vitamin D deficiency with dental caries in infants and children: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2024Pooled it
- Associations of Prenatal Vitamin D status with Oral Health in Offspring: A Systematic Review.Oral health & preventive dentistry · 2022Pooled it
- Prenatal or Childhood Serum Levels of Vitamin D and Dental Caries in Paediatric Patients: A Systematic Review.Oral health & preventive dentistry · 2020Pooled it
- Vitamin D Levels During Pregnancy and Dental Caries in Offspring.JAMA network open · 2025Article
- Iron Level in Pregnant Rats is Associated with Caries Susceptibility in Offsprings.Biological trace element research · 2025Article
- From cultural dispositions to biological dimensions: a narrative review on the synergy between oral health and vitamin D through the lens of Indian habitus.Frontiers in oral health · 2025Review
- The Role of Serum Vitamin D Levels and Vitamin D Receptor (Children (Basel, Switzerland) · 2024Article
- Association of Salivary Vitamin D and Vitamin C Levels with Dental Caries in Children: A Cross-sectional Study.International journal of clinical pediatric dentistry · 2024Article
- Unveiling the Novel Impact of Vitamin D Injections at Birth on the Prognosis of Newborns: A Double-blind Study.Oman medical journal · 2024Article
- The Influence of Vitamin D Levels on Dental Caries: A Retrospective Study of the United States Population.Nutrients · 2024Article
- The Impact of Vitamin Deficiencies on Oral Manifestations in Children.Dentistry journal · 2024Review
- Dental caries in children and vitamin D deficiency: a narrative review.European journal of pediatrics · 2024Review
- Association between Malnutrition and Dental Caries in Iraqi Kurdish Children.Dentistry journal · 2023Article
- Article
- Expert consensus on clinical management for early childhood caries.Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2022Article
- Article
- Neonatal stunting and early childhood caries: A mini-review.Frontiers in pediatrics · 2022Review
- Association between Vitamin D and Dental Caries in a Sample of Canadian and American Preschool-Aged Children.Nutrients · 2021Article
- Association of parental-reported vitamin D supplementation with dental caries of 3-year-old children in Poland: a cross-sectional study.Clinical oral investigations · 2021Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
Alaska Native (AN) children experience one of the highest reported rates of severe early childhood caries (S-ECC). Serum vitamin D concentrations in AN childbearing women in the Yukon Kuskokwim Delta (YKD) region have decreased since the 1960s to currently low levels, related to a decrease in traditional marine diet. Recent studies suggest an association between prenatal vitamin D (25(OH)D) concentrations in mothers and S-ECC in their infants. We used independent t tests to analyze the influence of prenatal 25(OH)D levels in YKD AN mothers on S-ECC in their children using data collected in the Maternal Organics Monitoring Study (MOMS). Maternal 25(OH)D levels were assessed at prenatal visits and in cord blood. We queried electronic dental records to assess early childhood caries (ECC) status using highest decayed, missing, filled, primary teeth (dmft) scores at 12 to 59 mo of age. We examined prenatal and cord blood for 76 and 57 mother/infant pairs, respectively. Children 12 to 35 mo of age with "deficient" cord blood (25(OH)D <30 nmol/L) had a mean dmft score twice as high as children who were "nondeficient" at birth (9.3 vs. 4.7; P = 0.002). There was no significant difference in mean dmft scores for children aged 36 to 59 mo with deficient versus nondeficient cord blood 25(OH)D (10.9 vs. 8.7 P = 0.14). There was no significant difference in mean dmft scores for children aged 12 to 35 mo whose mothers had "sufficient" versus "insufficient" 25(OH)D during prenatal visits (9.0 vs. 7.4; P = 0.48). In this small sample, children with deficient vitamin D levels in cord blood had a dmft score at 12 to 35 mo 2-fold higher than children with nondeficient cord blood. Maternal 25(OH)D may influence the primary dentition, and improving vitamin D status in pregnant women might affect ECC rates in their infants.
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Registered trials
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