SynthesisPloS one2019
Mode of delivery and preterm birth in subsequent births: A systematic review and meta-analysis.
Synthesis in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04554745 (The Assessment of Cervical Length and Thickness of Cesarean Section Scar as Predictors for Preterm Labor in Patients With Previous Cesarean Section), which is not on this map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Assessment of Cervical Length and Thickness of Cesarean Section Scar as Predictors for Preterm Labor in Patients With Previous Cesarean Section
Who cites it
30 citing papers in PubMed, 68 citations in OpenAlex.
- Risk factors for preterm birth in advanced maternal age pregnancies: a retrospective study.BMC pregnancy and childbirth · 2026Review
- Artificial Intelligence and Machine Learning for predicting Major Obstetric Emergencies: Current Evidence, Clinical Translation, and Future Directions.International journal of women's health · 2026Review
- Non-linear association between interpregnancy interval after vaginal delivery and singleton preterm birth: a retrospective cohort study.BMC pregnancy and childbirth · 2025Article
- Recurrence Risk of Pregnancy Complications in Twin and Singleton Deliveries.American journal of perinatology · 2025Article
- Article
- Obstetric and pregnancy-related factors associated with caesarean delivery in Bangladesh: a survey in Rajshahi district.BMJ open · 2025Article
- Associations between term cesarean delivery in the first pregnancy and second-pregnancy preterm delivery.Acta obstetricia et gynecologica Scandinavica · 2025Article
- Article
- Cesarean section and the gestational duration of subsequent pregnancies: A nationwide register-based cohort study.PloS one · 2025Article
- If the first child is breech, overall outcomes for families with two children are similar regardless of the mode of the first birth.Scientific reports · 2024Article
- Is It Possible to Prevent the Thanatogenetic Processes in Premature Babies?Clinics and practice · 2024Article
- Mode of birth in subsequent pregnancy when first birth was vacuum extraction or second stage cesarean section at a tertiary referral hospital in Uganda.BMC pregnancy and childbirth · 2024Article
- Exploring Risk Factors and Perinatal Outcomes of Preterm Birth in a Tertiary Care Hospital: A Comprehensive Analysis.Cureus · 2024Article
- Mode of Delivery and Neonatal Outcomes of Preterm Deliveries: A Retrospective Study in Greece.Medicina (Kaunas, Lithuania) · 2023Article
- Risk of Preterm Birth among Secundiparas with a Previous Cesarean due to a Failed Vacuum Delivery.Journal of clinical medicine · 2023Article
- Trends and risk of recurrent preterm birth in pregnancy cohorts in rural Bangladesh, 1990-2019.BMJ global health · 2023Article
- Cesarean delivery and risk of HIV vertical transmission in Southern Brazil, 2008-2018.AJOG global reports · 2023Article
- Prevalence of preterm birth and associated factors among mothers who gave birth in public hospitals of east Gojjam zone, Ethiopia.BMC pregnancy and childbirth · 2023Article
- Association between the Risk of Preterm Birth and Low Birth Weight with Periodontal Disease in Pregnant Women: An Umbrella Review.Dentistry journal · 2023Review
- Correlates of low birth weight and preterm birth in India.PloS one · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Preterm birth continues to be an important problem in modern obstetrics and a large public health concern and is related to increased risk for neonatal morbidity and mortality. The aim of this study was to evaluate the data in the literature to determine the relationships between mode of delivery (cesarean section and vaginal birth) in the first pregnancy and the risk of subsequent preterm birth from a multi-year population based cohorts (PROSPERO registration number: 42018090788). Five electronic databases were searched. Observational studies that provided mode of delivery and subsequent preterm birth were eligible. Ten cohort studies, involving 10333501 women, were included in this study. Compared with vaginal delivery, women delivering by previous cesarean section had a significantly higher risk of preterm birth in subsequent births (RR 1.10, 95%CI 1.01-1.20). After adjusting confounding factors, there was still statistical significance (aRR 1.12, 95%CI 1.01-1.24). However, both before and after adjustment, there was no difference among very preterm birth (RR 1.14, 95%CI 0.90-1.43; aRR 1.16, 95%CI 0.80-1.68; respectively). To the best of our knowledge, this is the first systematic review and meta-analysis that suggests previous cesarean section could increase the risk of preterm birth in subsequent pregnancies. The result could provide policy makers, clinicians, and expectant parents to reduce the occurrence of unnecessary cesarean section.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.