ArticleSexually transmitted diseases2019
Rapidly Spreading Human Immunodeficiency Virus Epidemic Among Older Males and Associated Factors: A Large-scale Prospective Cohort Study in Rural Southwest China.
Article in Sexually transmitted diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 44 citations in OpenAlex.
- Global Burden of HIV and Other Sexually Transmitted Infections in Older Men: A Trend Analysis Study.The world journal of men's health · 2026Article
- Prevalence, trends, and correlates of HIV, syphilis, and HCV infections among male attendees at STD clinics in Southwest China: a 13-year cross-sectional study (2010-2022).BMC infectious diseases · 2025Article
- Impact of HIV Pretreatment Drug Resistance on Secondary Transmission Through Treatment Dropout: A Prospective Population-Based Study in Southwestern China.Infection and drug resistance · 2025Article
- The trend, prevalence and potential risk factors of secondary HIV transmission among HIV/AIDS individuals receiving ART in Guangxi, China: a longitudinal cross-sectional study.Emerging microbes & infections · 2024Article
- Characteristics of and Factors Associated With Partner Service Uptake Cascade Among People With Newly Reported HIV/AIDS Diagnoses in Southeastern China in 2022: Cross-Sectional Survey.JMIR public health and surveillance · 2024Article
- Effectiveness of human immunodeficiency virus prevention strategies by mapping the geographic dispersion pattern of human immunodeficiency virus prevalence in Nanning, China.BMC public health · 2024Article
- Diagnostic performance evaluation of urine HIV-1 antibody rapid test kits in a real-life routine care setting in China.BMJ open · 2024Article
- HIV transmission and associated factors under the scale-up of HIV antiretroviral therapy: a population-based longitudinal molecular network study.Virology journal · 2023Article
- Transmission network and phylogenetic analysis reveal older male-centered transmission of CRF01_AE and CRF07_BC in Guangxi, China.Emerging microbes & infections · 2023Article
- Epidemiology and Clinical Outcomes of HIV Infection in South-Central China: A Retrospective Study From 2003 to 2018.Frontiers in public health · 2022Article
- Genetic network analysis of human immunodeficiency virus sexual transmission in rural Southwest China after the expansion of antiretroviral therapy: A population-based study.Frontiers in microbiology · 2022Article
- Depression and Associated Factors Among Men Living with HIV/AIDS Aged 50 Years and Over in Chongqing, China.Journal of multidisciplinary healthcare · 2022Article
- Research Progress in the Epidemiology of HIV/AIDS in China.China CDC weekly · 2021Article
- The Risk of HIV/STDs Infection and Transmission Among Never-Married Male Migrants in China: Is Risk Attributable to Bachelorhood or Migration?Archives of sexual behavior · 2021Article
- A thematic analysis of experiences of HIV risks among female sex workers in the Yunnan-Vietnam Chinese border region.BMC women's health · 2021Article
- The origin and spread of CRF85_BC, driven by heterosexual transmission among older people in Sichuan, China.BMC infectious diseases · 2020Article
- Independent Risk Factors for Deaths due to AIDS in Chongqing, China: Does Age Matter?Frontiers in medicine · 2020Article
- Evolving HIV Epidemiology in Mainland China: 2009-2018.Current HIV/AIDS reports · 2019Review
- HIV Epidemiology and Prevention in Southwestern China: Trends from 1996-2017.Current HIV research · 2019Review
- Higher Risks of Virologic Failure and All-Cause Deaths Among Older People Living with HIV in Chongqing, China.AIDS research and human retrovirusesArticle
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIncreasing risk of human immunodeficiency virus (HIV) heterosexual transmission can raise the potential for a more diffuse and generalized epidemic. In response to the paucity of data on HIV incidence among heterosexuals in China, we conducted a large-scale, population-based cohort study located in rural southwest China.
methodsBaseline enrollment for the study was conducted from 2013 to 2014 and follow-up at 12 months was from 2014 to 2015 among adults 20 years or older in 3 rural counties of Southwest China. Study participants were informed of the study by brochures and leaflets distributed in outreach activities. Interviews and blood collection were conducted in private rooms. Blood samples were tested for HIV infection.
resultsThe HIV prevalence of the sample was 0.29% (95% confidence interval [CI], 0.27-0.30) (2063 of 722,795) among the total adult population of 1,090,296 potential participants 20 years or older at baseline. Of the 720,732 individuals who tested HIV-negative at baseline, 493,990 (69%) completed the follow-up. Overall HIV incidence was 2.73 (95% CI, 2.38-3.08) per 10,000 person-years (PY) (235 of 860,627 PY). Human immunodeficiency virus incidence was associated with males, older age, less than secondary schooling and not currently being married. Human immunodeficiency virus incidence was 71.28 (95% CI, 35.21-107.35) per 10,000 PY among males aged 50 to 69 years who had less than secondary schooling and were divorced or widowed. Heterosexual sex was the dominant transmission mode for HIV seroconversions (99.0%).
conclusionsOlder heterosexual males were at disproportionate risk of HIV infection. Health authorities in China need to develop and implement innovative interventions suitable for the broader population of older heterosexuals.
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