Evidence map›Paper›PMID 30870305›Full record

ArticleJournal of thoracic imaging2019

Added Value of Ultra-low-dose Computed Tomography, Dose Equivalent to Chest X-Ray Radiography, for Diagnosing Chest Pathology.

Lucia J M Kroft, Levinia van der Velden, Irene Hernández Girón, Joost J H Roelofs, Albert de Roos, Jacob Geleijns

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Journal of thoracic imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04645030 (The Value of Ultralow Dosis CT and Ultrasound in the Diagnosing of Pneumonia in the Emergency Department), which is not on this map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
13.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04645030 completednot on this mapstarted 2021, after this paper: background citation

The Value of Ultralow Dosis CT and Ultrasound in the Diagnosing of Pneumonia in the Emergency Department

TypeobservationalSponsorUniversity of Southern DenmarkRan2021 to 2022Enrolled411ConditionsRespiratory Tract InfectionsArmsUltra low-dose computer thermography, lung ultrasound
3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 123 citations in OpenAlex.

  1. Trial
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  6. Review
  7. Towards ultra-low-dose CT for detecting pulmonary nodules using DenseNet.Physical and engineering sciences in medicine · 2025
    Article
  8. Article
  9. Are radiographs overutilized in pediatric orthopaedic emergency room care?Journal of the Pediatric Orthopaedic Society of North America · 2024
    Article
  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Lucia J M KroftDepartment of Radiology, Leiden University Medical Center, Leiden, The Netherlands.
Levinia van der Velden
Irene Hernández Girón
Joost J H Roelofs
Albert de Roos
Jacob Geleijns
Leiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study was to assess the clinical value of ultra-low-dose computed tomography (ULDCT) compared with chest x-ray radiography (CXR) for diagnosing chest pathology. MATERIALS AND

methodsA total of 200 patients referred for CXR by outpatient clinics or general practitioners were enrolled prospectively. They underwent CXR (posteroanterior and lateral) and ULDCT (120 kV, 3 mAs) on the same day. In-room time and effective dose were recorded for each examination. Studies were categorized whether they were diagnostic or not, relevant radiologic diagnostic findings were reported, and confidence for diagnosis was recorded by a Likert scale. Differences in diagnostic confidence and effect on management decision were compared.

resultsIn-room time was <2 minutes for CXR and <3 minutes for ULDCT. Effective dose was 0.040 mSv for CXR and 0.071 mSv for ULDCT. CXR was considered diagnostic in 98% and ULDCT in 100%. The mean perceived confidence for diagnosis was 88±12% with CXR and 98±2% with ULDCT (P<0.0001), whereas discrepant findings between CXR and ULDCT were found in 101 of 200 patients. As compared with CXR, ULDCT had added value for management decisions in 40 of 200 patients.

conclusionsULDCT provided added value to the radiologist by improved perceived confidence with a reduction in false-positive and false-negative CXR investigations that had management implications in 20% of patients. The effective dose of ULDCT will not be a limiting factor for introducing ULDCT of the chest on a broad scale in clinical practice.

Indexed as

Radiation DosageAgedAged, 80 and overFemaleHumansLungLung NeoplasmsMaleMiddle AgedProspective StudiesRadiographic Image Interpretation, Computer-AssistedRadiographyRadiography, ThoracicTomography, X-Ray Computed

Identifiers

PMID30870305
PMCPMC6485307
OpenAlexW2921237545

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.