ArticleAutophagy2019
METTL3 and ALKBH5 oppositely regulate m
Open access · bronzeAbstract read
In one paragraph
Article in Autophagy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 311 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
311citing papers in PubMed, 1 pooled it
26.1field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
311 citing papers in PubMed, 1 synthesis or guideline pooled it, 533 citations in OpenAlex.
- RNA methylation in vascular disease: a systematic review.Journal of cardiothoracic surgery · 2022Pooled it
- circNLK restrains glioblastoma malignancy by binding to hnRNP L and destabilizing RGS16.Non-coding RNA research · 2026Article
- SEC Mediates mAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- METTL3 Confers Ischemia/Reperfusion-Caused Myocardial Injury by Triggering Ferroptosis via Regulating the lncRNA SNHG14/miR-195a-5p/ACSL4 Axis.Cardiovascular drugs and therapy · 2026Article
- Cell death in ischemia-reperfusion injury: beyond a single-cell-death perspective.Biomarker research · 2026Review
- METTL14-Mediated N6-Methyladenosine Exacerbates Acute Lung Injury via USP30/NCOA4-Dependent Ferroptosis.MedComm · 2026Article
- PDE4D Mediates the Cardiac Ischemia Reperfusion Injury and Is m6A Modified by METTL14.Korean circulation journal · 2026Article
- Article
- Article
- HNRNPC as a Novel Therapeutic Target for Ischemic Heart Disease: Evidence From Mendelian Randomization and Experimental Validation.Journal of the American Heart Association · 2026Article
- PYRIN mActa pharmacologica Sinica · 2026Article
- Transcriptional and epigenetic regulation of autophagy: mechanisms, disease relevance and therapeutic opportunities.Signal transduction and targeted therapy · 2026Review
- The Role of NMedComm · 2026Review
- RNA-binding protein hnRNPK: a multifunctional regulator of skeletal muscle biology and disease.Biochemical Society transactions · 2026Review
- The role of N6-methyladenosine associated genes in ischemic stroke risk: interplay with environmental factors.Journal of thrombosis and thrombolysis · 2026Review
- Emerging roles of RNA mInternational journal of oncology · 2026Review
- The N6-Methyladenosine RNA Demethylase AlkB Homolog 5 (ALKBH5) in Metabolic Diseases: Molecular Mechanisms and Pharmacological Implications-A Review.Biomolecules · 2026Review
- METTL3-mediated N6-methyladenosine modification ofProceedings of the National Academy of Sciences of the United States of America · 2026Article
- ALKBH5-Driven m6A Demethylation Boosts Inflammation and Autophagy in LPS-Stimulated Macrophages.Immunity, inflammation and disease · 2026Article
- m6A RNA modification and its emerging roles in diseases: recent advances and therapeutic implications.Journal of translational medicine · 2026Review
251 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 10 institutions in 2 countries.
Huiwen Songa Longju Medical Research Center; Key Laboratory of Basic Pharmacology of Ministry of Education , Zunyi Medical University , Zunyi , China.
Xing Fenga Longju Medical Research Center; Key Laboratory of Basic Pharmacology of Ministry of Education , Zunyi Medical University , Zunyi , China.ORCID 0000-0001-8226-3389
Heng Zhangd Department of Histology and Embryology, Xiang Ya School of Medicine , Central South University , Changsha , China.
Yunmei Luoa Longju Medical Research Center; Key Laboratory of Basic Pharmacology of Ministry of Education , Zunyi Medical University , Zunyi , China.
Juan Huanga Longju Medical Research Center; Key Laboratory of Basic Pharmacology of Ministry of Education , Zunyi Medical University , Zunyi , China.
Meihua Line Research Center of Clinical Pharmacy, State Key Laboratory for Diagnosis and Treatment of Infectious Disease, First Affiliated Hospital , Zhejiang University , Hangzhou , China.
Junfei Jinf Laboratory of Hepatobiliary and Pancreatic Surgery , Affiliated Hospital of Guilin Medical University , Guilin , China.
Xue Dingg Department of Cardiology; the First Affiliated Hospital , Harbin Medical University , Harbin , China.
Shujing Wuh Department of Cardiology , The ChengGong Hospital Affiliated to Xiamen University , Xiamen , China.
He Huangd Department of Histology and Embryology, Xiang Ya School of Medicine , Central South University , Changsha , China.
Tian Yuj Department of Anesthesia , Affiliated Hospital of Zunyi Medical University , Zunyi , China.
Mukun Zhangk Health Management Center , The First Affiliated Hospital of USTC (Anhui Provincial Hospital) , Hefei , China.
Haiou Hongk Health Management Center , The First Affiliated Hospital of USTC (Anhui Provincial Hospital) , Hefei , China.
Shihua Yaol Department of Thoracic Surgery, Changhai Hospital , Second Military Medical University , Shanghai , China.
Yongxiang Zhaom National Center for International Research of Biological Targeting Diagnosis and Therapy (Guangxi Key Laboratory of Biological Targeting Diagnosis and Therapy Research) , Guangxi Medical University , Nanning , China.
Zhiyong Zhanga Longju Medical Research Center; Key Laboratory of Basic Pharmacology of Ministry of Education , Zunyi Medical University , Zunyi , China.ORCID 0000-0001-8576-1607
Zunyi Medical University · CNAnhui Provincial Hospital · CNCentral South University · CNRutgers, The State University of New Jersey · USFirst Affiliated Hospital Zhejiang University · CNGuangxi Medical University · CNGuilin Medical University · CNHarbin Medical University · CNSecond Military Medical University · CNXiamen University · CN
Funding
No grant is acknowledged in the PubMed record.
Abstract
N
Indexed as
AdenosineAlkB Homolog 5, RNA DemethylaseAlpha-Ketoglutarate-Dependent Dioxygenase FTOAnimalsApoptosisAutophagyBase SequenceBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsCell HypoxiaHEK293 CellsHeterogeneous-Nuclear Ribonucleoprotein DHumansMethylationMethyltransferasesMiceMyocytes, CardiacAdenosineAlkB Homolog 5, RNA DemethylaseAlpha-Ketoglutarate-Dependent Dioxygenase FTOBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsFTO protein, mouseHeterogeneous-Nuclear Ribonucleoprotein DMethyltransferasesMettl3 protein, mouseN-methyladenosineOxygenRNA, MessengerRNA PrecursorsTcfeb protein, mouseALKBH5cardiomyocytesHNRNPDhypoxia/reoxyogenationmA modificationMETTL3
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.