Evidence map›Paper›PMID 30869926›Full record

ArticleJournal of abnormal psychology2019

Alterations in facial expressivity in youth at clinical high-risk for psychosis.

Tina Gupta, Claudia M Haase, Gregory P Strauss, Alex S Cohen, Vijay A Mittal

Abstract read
In one paragraph

Article in Journal of abnormal psychology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Humanizing "multimodal" digital phenotyping of serious mental illness.Journal of psychopathology and clinical science · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tina GuptaDepartment of Psychology, Northwestern University.
Claudia M HaaseDepartment of Psychology, Northwestern University.
Gregory P StraussDepartment of Psychology, University of Georgia.
Alex S CohenDepartment of Psychology, Louisiana State University.ORCID 0000-0003-4014-6904
Vijay A MittalDepartment of Psychology, Northwestern University.ORCID 0000-0001-9017-5119

Funding

TRAINING PROGRAM IN THE NEUROSCIENCE OF HUMAN COGNITIONT32NS047987 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Rodrigo M Braga, Christina Maria Zelano · 2006 to 2026
$5.6M
Frontal-Subcortical Development, Movement Abnormalities, and Risk for PsychosisR01MH094650 · NIMH · UNIVERSITY OF COLORADO · PI MITTAL, VIJAY A · 2011 to 2015
$2.3M
High-Risk Psychosis Youth and Caregivers: Emotion in InteractionR21MH115231 · NIMH · NORTHWESTERN UNIVERSITY · PI HAASE, CLAUDIA, MITTAL, VIJAY A · 2017 to 2018
$484k
Neural Habituation in Ultra High-Risk YouthR21MH110374 · NIMH · NORTHWESTERN UNIVERSITY · PI MITTAL, VIJAY A · 2017 to 2018
$445k
National Institute of Mental HealthNIMH NIH HHS R01 MH094650NIMH NIH HHS R21 MH110374NIMH NIH HHS R21 MH115231NINDS NIH HHS T32 NS047987
6 · The paper itself

Abstract

Negative symptoms, such as blunted facial affect, are core features of psychotic disorders that predict poor functional outcome. However, it is unknown whether these impairments occur prior to the onset of psychosis. Understanding this phenomenon in the psychosis risk period has significant relevance for elucidating pathogenic processes, as well as potential for informing a viable new behavioral marker for broader social dysfunction and clinical course. The current study sought to determine the nature of facial expression deficits among individuals at clinical high-risk (CHR) for developing psychosis using a comprehensive approach, incorporating clinical interview ratings and automated facial expression coding analysis. A total of 42 CHR and 42 control participants completed clinical interviews and digitally taped segments were submitted into an automated, computerized tool to assess for 7 facial expressions (joy, anger, surprise, fear, contempt, disgust, sadness). Furthermore, relationships between facial expressions and social functioning and available scores on a psychosis conversion risk calculator from a total of 78 participants (39 CHR and 39 controls) were examined. Relationships between measures were also investigated (data was available for the Prodromal Inventory of Negative Symptoms among 33 CHR and 25 controls). Findings from clinical interview indicated that the CHR group exhibited elevated blunting. Furthermore, automated analyses showed that the CHR group displayed blunting in expressions of joy but surprisingly, increased anger facial expressions. Lastly, irregularities in facial expressions were related to decreased social functioning and increased psychosis conversion risk calculator scores, signaling heightened likelihood of conversion to psychosis. These findings suggest that alterations in facial expressivity occur early in the pathogenesis of psychosis and provide evidence for the efficacy of higher resolution measures of facial expressivity in psychosis research. (PsycINFO Database Record (c) 2019 APA, all rights reserved).

Indexed as

AffectFacial ExpressionRisk AssessmentAdolescentAdultCase-Control StudiesChildFemaleHumansInterview, PsychologicalMaleProdromal SymptomsPsychotic DisordersSocial AdjustmentYoung Adult

Identifiers

PMID30869926
PMCPMC6499690

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.