Evidence map›Paper›PMID 30869044›Full record

ArticleEpidemiology and infection2019

Chronic hepatitis B and C infections in the Netherlands: estimated prevalence in risk groups and the general population.

J Koopsen, J E van Steenbergen, J H Richardus, M Prins, E L M Op de Coul, E A Croes, J Heil, F R Zuure, I K Veldhuijzen

Open access · hybridAbstract read
In one paragraph

Article in Epidemiology and infection, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Article
  3. Use of the Workbook Method to estimate the prevalence of chronic hepatitis B infections in the European Union and European Economic Area, 2022.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026
    Article
  4. Article
  5. Article
  6. Estimated prevalence of hepatitis B and C among immigrants in Canada.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

J KoopsenCenter for Infectious Disease Control,National Institute for Public Health and the Environment (RIVM),Bilthoven,The Netherlands.ORCID 0000-0002-5723-6933
J E van SteenbergenCenter for Infectious Disease Control,National Institute for Public Health and the Environment (RIVM),Bilthoven,The Netherlands.
J H RichardusDepartment of Public Health,Erasmus MC, University Medical Center Rotterdam,Rotterdam,The Netherlands.
M PrinsDepartment of Infectious Diseases,Research and Prevention, Public Health Service of Amsterdam,Amsterdam,The Netherlands.
E L M Op de CoulCenter for Infectious Disease Control,National Institute for Public Health and the Environment (RIVM),Bilthoven,The Netherlands.
E A CroesNetherlands Institute of Mental Health and Addiction (Trimbos Institute),Utrecht,The Netherlands.
J HeilDepartment of Sexual Health,Infectious Diseases and Environmental Health, Municipal Public Health Service South Limburg,Geleen,The Netherlands.
F R ZuureDepartment of Infectious Diseases,Research and Prevention, Public Health Service of Amsterdam,Amsterdam,The Netherlands.
I K VeldhuijzenCenter for Infectious Disease Control,National Institute for Public Health and the Environment (RIVM),Bilthoven,The Netherlands.
National Institute for Public Health and the Environment · NLAmsterdam UMC Location University of Amsterdam · NLErasmus MC · NLLeiden University Medical Center · NLMaastricht University · NLTrimbos Institute · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are usually asymptomatic for decades, thus targeted screening can prevent liver disease by timely diagnosis and linkage to care. More robust estimates of chronic HBV and HCV infections in the general population and risk groups are needed. Using a modified workbook method, the total number of ever chronically infected individuals in the Netherlands in 2016 was determined using population size and prevalence estimates from studies in the general and high-risk population. The estimated 2016 chronic HBV infection prevalence is 0.34% (low 0.22%, high 0.47%), corresponding to approximately 49 000 (low 31 000, high 66 000) HBV-infected individuals aged 15 years and older. The estimated ever-chronic HCV infection prevalence is 0.16% (low 0.06%, high 0.27%), corresponding to approximately 23 000 (low 8000, high 38 000) ever-chronic HCV-infected individuals. The prevalence of chronic HBV and HCV infections in the Netherlands is low. First-generation migrants account for most infections with 81% and 60% of chronic HBV and HCV infections, respectively. However, about one-fifth of HCV infections is found in the general population at low risk. This method can serve as an example for countries in need of more accurate prevalence estimates, to help the design and evaluation of prevention and control policies.

Indexed as

FemaleHepatitis B, ChronicHepatitis C, ChronicHumansMaleNetherlandsPrevalenceRisk Assessmenthepatitis B virushepatitis C virusmigrantsprevalence

Identifiers

PMID30869044
PMCPMC6518512
OpenAlexW2920850762

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.