Evidence map›Paper›PMID 30869031›Full record

ArticleEpidemiology and infection2019

Has Chlamydia trachomatis prevalence in young women in England, Scotland and Wales changed? Evidence from national probability surveys.

D Z Kounali, N J Welton, K Soldan, S C Woodhall, J Kevin Dunbar, S J Migchelsen, C H Mercer, P Horner, A E Ades

Abstract read
In one paragraph

Article in Epidemiology and infection, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
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  3. Article
  4. Letter to editor in response to HasEpidemiology and infection · 2019
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

D Z KounaliPopulation Health Sciences, Bristol Medical School,Oakfield House, Oakfield Grove, Bristol BS8 5BN,UK.ORCID 0000-0002-6392-6690
N J WeltonPopulation Health Sciences, Bristol Medical School,Oakfield House, Oakfield Grove, Bristol BS8 5BN,UK.
K SoldanNational Institute for Health Research Health Protection Research Unit in Evaluation of Interventions, University of Bristol,Bristol,UK.
S C WoodhallBlood Safety, Hepatitis, Sexually Transmitted Infections and HIV Division,Public Health England, London, 61 Colindale Avenue, London NW9 5EQ,UK.
J Kevin DunbarBlood Safety, Hepatitis, Sexually Transmitted Infections and HIV Division,Public Health England, London, 61 Colindale Avenue, London NW9 5EQ,UK.
S J MigchelsenBlood Safety, Hepatitis, Sexually Transmitted Infections and HIV Division,Public Health England, London, 61 Colindale Avenue, London NW9 5EQ,UK.
C H MercerInstitute for Global Health, University College London, Mortimer Market Centre,London, WC1E 6JB,UK.
P HornerPopulation Health Sciences, Bristol Medical School,Oakfield House, Oakfield Grove, Bristol BS8 5BN,UK.
A E AdesPopulation Health Sciences, Bristol Medical School,Oakfield House, Oakfield Grove, Bristol BS8 5BN,UK.

Funding

Medical Research Council G0701757Medical Research Council G0801947Medical Research Council MR/R015600/1
6 · The paper itself

Abstract

We evaluate the utility of the National Surveys of Attitudes and Sexual Lifestyles (Natsal) undertaken in 2000 and 2010, before and after the introduction of the National Chlamydia Screening Programme, as an evidence source for estimating the change in prevalence of Chlamydia trachomatis (CT) in England, Scotland and Wales. Both the 2000 and 2010 surveys tested urine samples for CT by Nucleic Acid Amplification Tests (NAATs). We examined the sources of uncertainty in estimates of CT prevalence change, including sample size and adjustments for test sensitivity and specificity, survey non-response and informative non-response. In 2000, the unadjusted CT prevalence was 4.22% in women aged 18-24 years; in 2010, CT prevalence was 3.92%, a non-significant absolute difference of 0.30 percentage points (95% credible interval -2.8 to 2.0). In addition to uncertainty due to small sample size, estimates were sensitive to specificity, survey non-response or informative non-response, such that plausible changes in any one of these would be enough to either reverse or double any likely change in prevalence. Alternative ways of monitoring changes in CT incidence and prevalence over time are discussed.

Indexed as

AdolescentAdultChlamydia InfectionsChlamydia trachomatisEnglandFemaleHumansIncidenceNucleic Acid Amplification TechniquesPrevalenceScotlandWalesYoung AdultChlamydia trachomatisprevalencesexually transmitted infections (STIs)

Identifiers

PMID30869031
PMCPMC6518515

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.