ArticleEpidemiology and infection2019
Dengue, chikungunya and zika virus coinfection: results of the national surveillance during the zika epidemic in Colombia.
Article in Epidemiology and infection, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 4 of them syntheses that pooled it.
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Who cites it
49 citing papers in PubMed, 4 syntheses or guidelines pooled it, 89 citations in OpenAlex.
- The Epidemiological Impact of Dengue in Colombia: A Systematic Review.The American journal of tropical medicine and hygiene · 2025Pooled it
- The global epidemiology of chikungunya from 1999 to 2020: A systematic literature review to inform the development and introduction of vaccines.PLoS neglected tropical diseases · 2022Pooled it
- Clinical manifestations and health outcomes associated with Zika virus infections in adults: A systematic review.PLoS neglected tropical diseases · 2021Pooled it
- The frequency and clinical presentation of Zika virus coinfections: a systematic review.BMJ global health · 2020Pooled it
- Detection of Dengue Virus and Serological Evidence of Chikungunya and Zika Virus Exposure in Patients with Acute Febrile Syndrome in Córdoba, Colombia.Tropical medicine and infectious disease · 2026Article
- Analytical and Clinical Evaluation of the STANDARD M10 Arbovirus Panel for Dengue Detection, Serotyping, and Multiplex Arboviral Screening in the Americas.Diagnostics (Basel, Switzerland) · 2026Article
- Mathematical modeling and analysis of the Dengue and Chikungunya co-infection.Scientific reports · 2026Article
- A Global Perspective on the Emerging Threat of Zika and Dengue Co-infection.PLoS neglected tropical diseases · 2026Article
- Oropouche fever: Clinical characteristics and viral-bacterial coinfections in a region of the Peruvian Amazon: A cross-sectional study.IJID regions · 2025Article
- Spatio-temporal analysis of the distribution and co-circulation of dengue, chikungunya, and Zika in Medellín, Colombia, from 2013 to 2021.PLoS neglected tropical diseases · 2025Article
- Dengue and Flavivirus Co-Infections: Challenges in Diagnosis, Treatment, and Disease Management.International journal of molecular sciences · 2025Review
- Exploring Zika's dynamics: A scoping review journey from epidemic to equations through mathematical modelling.Infectious Disease Modelling · 2025Review
- Effect of chikungunya, Mayaro and Una virus coinfection on vector competence ofOne health (Amsterdam, Netherlands) · 2025Article
- Harnessing engineered symbionts to combat concurrent malaria and arboviruses transmission.Nature communications · 2025Article
- Coinfection with chikungunya and Zika results in mild disease and distinct inflammatory response.Npj viruses · 2025Article
- WNV and SLEV coinfection in avian and mosquito hosts: impact on viremia, antibody responses, and vector competence.Journal of virology · 2024Article
- Conjugates of ibuprofen inhibit CHIKV infection and inflammation.Molecular diversity · 2024Article
- Review
- Exploring Zika Virus Impact on Endothelial Permeability: Insights into Transcytosis Mechanisms and Vascular Leakage.Viruses · 2024Review
- Global Prevalence of Zika and Chikungunya Coinfection: A Systematic Review and Meta-Analysis.Diseases (Basel, Switzerland) · 2024Review
Corrections and comments
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Authors and funding
15 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Our objective was to determine the frequency of zika (ZIKV), chikungunya (CHIKV) and dengue (DENV) virus coinfection and describe the mortality cases that occurred during the epidemiologic surveillance of the ZIKV epidemic in Colombia. We analysed all cases of suspected ZIKV infection that were reported to the National Institute of Health (October 2015-December 2016). DENV, CHIKV and ZIKV RNA were detected in serum or tissue samples using polymerase chain reaction assay. Medical records of the fatal cases were reviewed. We identified that 23 871 samples were processed. The frequency of viral agents was 439 (1.84%) for DENV, 257 (1.07%) for CHIKV and 10118 (42.38%) for ZIKV. Thirty-four (0.14%) cases of coinfection were identified. The CHIKV-ZIKV coinfection was present in 28 cases (82.3%), DENV-CHIKV in three (8.8%) and DENV-ZIKV in three (8.8%). Seven (20.6%) coinfection cases were fatal (two DENV-CHIKV cases and five CHIKV-ZIKV cases). Two cases were foetal deaths and the others were related to neurological syndrome and sepsis. In conclusion, the frequency of arbovirus coinfection during epidemic of ZIKV was low, and CHIKV-ZIKV coinfection was the most common. Mortality was high among coinfection patients. The role of each virus in the mortality cases of coinfection warrants further studies.
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